Active Recombinant Mouse Tnfrsf13b Protein, Fc-tagged

• Cat.No.: Tnfrsf13b-6545M
• Product Overview: Purified recombinant protein of Mouse tumor necrosis factor receptor superfamily, member 13b (Tnfrsf13b) with a Fc tag was expressed in HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Fc
• Protein Length: Met1-Thr129
• Description: Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
• Bio-activity: The ED50 is 5 - 10 ng/mL, corresponding to a specific activity of 1.0-2.0 × 10^5 units/mg, determined by inhibition of BAFF mediated B cell proliferation by mouse TACI-Fc in a dose dependent manner. B cells were activated with anti-IgM
• Molecular Mass: 41 kDa
• Endotoxin: Less than 0.01 ng/μg protein as determined by the LAL method
• Purity: > 98%, as determined by Coomassie stained SDS-PAGE.
• Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 1 x PBS

Gene Information

• Gene Name: Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b [ Mus musculus (house mouse) ]
• Official Symbol: Tnfrsf13b
• Synonyms: TNFRSF13B; tumor necrosis factor receptor superfamily, member 13b; tumor necrosis factor receptor superfamily member 13B; transmembrane activator and CAML interactor; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; Taci; 1200009E08Rik
• Gene ID: 57916
• mRNA Refseq: NM_021349
• Protein Refseq: NP_067324
• UniProt ID: Q9ET35