tnfsf13b
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  • Official Full Name
  • tumor necrosis factor (ligand) superfamily, member 13b
  • Background
  • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
  • Synonyms
  • DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; tumor necrosis factor ligand superfamily member 13B; delta BAFF; Delta4 BAFF; B-lymphocyte stimulator; B-cell-activating factor; ApoL related ligand TALL-1; TNF homolog that activates apoptosis; dendritic cell-derived TNF-like molecule; tumor necrosis factor-like protein ZTNF4; TNF and ApoL-related leukocyte expressed ligand 1; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor superfamily, member 13b; tumor necrosis factor superfamily, member 13b; TNFSF13B; CD257 antigen
Cat.#:TNFSF13B-333HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFSF13B Protein (Ala134-Leu285)
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Cat.#:TNFSF13B-377HTag:His & Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B Protein, His & Avi-tagged, Biotinylated
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Cat.#:TNFSF13B-378MTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse TNFSF13B Protein
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Cat.#:TNFSF13B-379MTag:MIgG2a Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse TNFSF13B Protein, MIgG2a Fc-tagged, low endotoxin
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Cat.#:TNFSF13B-2021HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B Protein, MYC/DDK-tagged
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Cat.#:TNFSF13B-2026MTag:
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse TNFSF13B Protein
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Cat.#:TNFSF13B-301HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Tumor Necrosis Factor (ligand) Superfamily, Member 13B
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Cat.#:TNFSF13B-004HTag:Fc
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TNFSF13B Protein, Fc-tagged
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Cat.#:TNFSF13B-005HTag:
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TNFSF13B Protein
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Cat.#:TNFSF13B-135HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B
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Cat.#:TNFSF13B-140HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human TNFSF13B Active, His-tagged
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Cat.#:TNFSF13B-1547HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant human TNFSF13B, Active, His-tagged
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Cat.#:TNFSF13B-1818HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B protein, His-tagged
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Cat.#:TNFSF13B-1819HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B protein, Fc-tagged, FITC-Labeled
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Cat.#:TNFSF13B-184HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFSF13B, His-tagged
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Cat.#:TNFSF13B-1902HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human TNFSF13B
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Cat.#:TNFSF13B-219HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFSF13B protein, His/S-tagged
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Cat.#:TNFSF13B-22HTag:Flag
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BAFF soluble, FLAG-tagged
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Cat.#:TNFSF13B-244HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human TNFSF13B, Fc-tagged
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Cat.#:TNFSF13B-26301THTag:Flag
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFSF13B, FLAG-tagged
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Cat.#:TNFSF13B-26302THTag:
Source (Host):Species:Human
Product nameRecombinant Human TNFSF13B
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Cat.#:TNFSF13B-27431THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFSF13B
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Cat.#:TNFSF13B-423HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B, Fc tagged
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Cat.#:TNFSF13B-425HTag:Fc/Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B Protein, Fc & Avi-tagged, Biotinylated
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Cat.#:TNFSF13B-445HTag:His/Fc
Source (Host):HEK293FSpecies:Human
Product nameRecombinant Human TNFSF13B protein, His & Fc-tagged
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Cat.#:TNFSF13B-551HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B, None tagged
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Cat.#:TNFSF13B-552HTag:Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B Protein, Avi-tagged, Biotinylated
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Cat.#:TNFSF13B-567HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFSF13B
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Cat.#:TNFSF13B-933HTag:DDK/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TNFSF13B Protein, DDK/His-tagged
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Cat.#:Tnfsf13b-119MTag:Flag
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Tnfsf13b, FLAG-tagged
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Cat.#:Tnfsf13b-1803MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tnfsf13b protein, His-tagged
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Cat.#:Tnfsf13b-220RTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tnfsf13b protein, His/S-tagged
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Cat.#:Tnfsf13b-221RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tnfsf13b protein, His/S-tagged
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Cat.#:TNFSF13B-136CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus TNFSF13B, Fc tagged
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Cat.#:TNFSF13B-1059CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine TNFSF13B Protein, Fc-tagged
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Cat.#:TNFSF13B-5900CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TNFSF13B
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Cat.#:TNFSF13B-6327ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TNFSF13B
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Cat.#:TNFSF13B-352HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Tumor Necrosis Factor (Ligand) Superfamily, Member 13b
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Cat.#:TNFSF13B-395HTag:His
Source (Host):Nicotiana benthamianaSpecies:Human
Product nameRecombinant Human Tumor Necrosis Factor (ligand) Superfamily, Member 13b, His-tagged
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Cat.#:TNFSF13B-2025HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFSF13B cell lysate
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Cat.#:TNFSF13B-1014CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus TNFSF13B cell lysate
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Cat.#:TNFSF13B-P07HTag:
Source (Host):Species:Human
Product nameRecombinant Human TNFSF13B therapeutic protein
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Involved Pathway

TNFSF13B involved in several pathways and played different roles in them. We selected most pathways TNFSF13B participated on our site, such as Cytokine Signaling in Immune system, Cytokine-cytokine receptor interaction, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFSF13B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
CNKSR1; TRIM3; NOD1; IFI6; CRK; SPNA1; NUP50; RASGRP1; CASPBL; SPRED3
Cytokine-cytokine receptor interaction
TNFRSF21; IL11RA2; CCL2; THPO; CCL15; ACVR1L; INHBC; IL1R2; Fasl; VEGFAB
Immune System
OSBPL1A; TIRAP; DEFB119; EDAR; NLRC5; CD200R2; FBXO27; CD180; CRP; CTSLL
Intestinal immune network for IgA production
TNFSF13B; TNFRSF13C
NF-kappa B signaling pathway
TRAF6; SYK; MAP3K14; BCL10; LTB; IL-8; PRKCB; TICAM2; TRAF2; IL1R1
Rheumatoid arthritis
HLA-DRB4; TNFSF13; ATP6V1D; H2-AA; ATP6V1E2; ITGAL; ATP6V1H; HLA-DMA; ITGB2; IL23
Spinal Cord Injury
PTPRZ1; MBP; TNFSF13B; NOX4; GAP43; GDNF; OMG; KLK8; AIF1; RTN4
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
TNFSF13B; TNFRSF13C

Protein Function

TNFSF13B has several biochemical functions, for example, cytokine activity, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFSF13B itself. We selected most functions TNFSF13B had, and list some proteins which have the same functions with TNFSF13B. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein MIF; GDF5; IL12BA; CMTM3; IFNPHI1; GM13289; WNT2; BMP7A; NDP; IL19
Function protein binding
Related Protein ARAP3; DDX55; HM13; RBX1; PES1; BATF2; LARP2; DCC; NUS1; EIF3E
Function receptor binding
Related Protein POU2F1; LRRC4B; TNFSF4; ACOX2; PVRL3B; Ifnl2; BMP3; GLA; CYTL1; DAO1
Function tumor necrosis factor receptor binding
Related Protein TNFSF15; TRAP1; TNFSF9; TNFB; CD70; ERAP1; TRADD; TRAF2; TNFSF10; TNFSF13B

Interacting Protein

TNFSF13B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFSF13B here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFSF13B.
TNFRSF13B; TNFRSF17

TNFSF13B Related Articles

Nocturne, G; Mariette, X; et al. Sjogren Syndrome-associated lymphomas: an update on pathogenesis and management. BRITISH JOURNAL OF HAEMATOLOGY 168:317-327(2015).
Pellkofer, HL; Krumbholz, M; et al. Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab. NEUROLOGY 76:1310-1315(2011).

TNFSF13B Related Gene Family

TNF Cytokines