Active Recombinant Human TNFSF13B Protein, N-His-tagged

• Cat.No.: TNFSF13B-24H
• Product Overview: Recombinant Human TNFSF13B Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
• Bio-activity: Measured by its binding ability in a functional ELISA with Human BAFFR.
• Molecular Mass: 21.4 kDa
• Protein Length: 190aa
• AA Sequence: MAV QGPEETVTQD CLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL
• N-terminal Sequence Analysis: 134-285aa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method).
• Purity: > 95% by SDS-PAGE
• Applications: SDS-PAGE, Bioactivity
• Usage: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay).

Gene Information

• Gene Name: TNFSF13B TNF superfamily member 13b [ Homo sapiens (human) ]
• Official Symbol: TNFSF13B
• Synonyms: DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20
• Gene ID: 10673
• mRNA Refseq: NM_006573.5
• Protein Refseq: NP_006564.1
• MIM: 603969
• UniProt ID: Q02223