Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Wnt5a

  • Official Full Name

    wingless-type MMTV integration site family, member 5A

  • Overview

    The Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transm
  • Synonyms

    WNT5A; wingless-type MMTV integration site family, member 5A; protein Wnt-5a; hWNT5A; WNT 5A protein; WNT-5A protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human/Mouse
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • L-Wnt-5a-expressing Mouse Fibroblast
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|GST
  • SUMO
  • DDK
  • Myc|DDK
  • N/A
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WNT5A-1634H Recombinant Human WNT5A protein, His-tagged E.coli His
Human WNT5A-2052H Recombinant Human WNT5A, GST-tagged Wheat Germ GST
Human WNT5A-206H Recombinant Human WNT5A, StrepII-tagged Human Cell Strep II 36-380, 345 a.a.
Human WNT5A-2055H Recombinant Human WNT5A, GST-tagged Wheat Germ GST
Human WNT5A-2053H Recombinant Human WNT5A, MYC/DDK-tagged HEK293 Myc/DDK
Human WNT5A-293HCL Recombinant Human WNT5A 293 Cell Lysate HEK293 N/A
Human WNT5A-3766H Recombinant Human WNT5A protein, His&Myc-tagged E.coli His&Myc 62-380aa
Human WNT5A-118H Active Recombinant Human WNT5A Protein E. coli
Human WNT5A-20H Recombinant Human WNT5A Protein, GST-tagged E.coli GST
Human WNT5A-11H Active Recombinant Human/Mouse Wnt-5a Protein, Biotinylated CHO
Human WNT5A-3768H Recombinant Human WNT5A protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc 62-380aa
Human WNT5A-546HF Recombinant Full Length Human WNT5A Protein, GST-tagged In Vitro Cell Free System GST 380 amino acids
Human WNT5A-2474H Recombinant Human WNT5A Protein (62-380 aa), His-tagged Yeast His 62-380 aa
Human WNT5A-5883H Recombinant Human WNT5A protein, His-tagged E.coli His 115-333aa
Human WNT5A-3765H Recombinant Human WNT5A protein, His-tagged E.coli His 62-380aa
Human WNT5A-195HFL Recombinant Full Length Human WNT5A Protein, C-Flag-tagged Mammalian cells Flag
Human WNT5A-2360H Recombinant Human WNT5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human WNT5A-2360H-B Recombinant Human WNT5A Protein Pre-coupled Magnetic Beads HEK293
Human WNT5A-2951H Recombinant Human WNT5A Protein (Ile62-Lys380), His tagged E.coli His Ile62-Lys380
Mouse WNT5A-19H Recombinant Mouse Wnt5a Protein, Gln38-Lys380 CHO Gln38-Lys380
Mouse Wnt5a-2054M Active Recombinant Mouse Wnt5a CHO N/A
Mouse Wnt5a-2055M Recombinant Mouse Wnt5a protein, His/GST-tagged E.coli His/GST Ile62~Lys380
Mouse Wnt5a-2051M Recombinant Mouse Wingless-Related MMTV Integration Site 5A L-Wnt-5a-expressing Mouse Fibroblast N/A
Mouse WNT5A-18573M Recombinant Mouse WNT5A Protein Mammalian Cell His
Mouse WNT5A-10198M Recombinant Mouse WNT5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Wnt5a-1492M Recombinant Mouse Wnt5a protein, GST-tagged E.coli GST Ile62~Lys380
Mouse Wnt5a-7006M Recombinant Mouse Wnt5a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Wnt5a-1493M Recombinant Mouse Wnt5a protein, His-tagged E.coli His Ile62~Lys380
Mouse WNT5A-10198M-B Recombinant Mouse WNT5A Protein Pre-coupled Magnetic Beads HEK293
Rat WNT5A-6600R Recombinant Rat WNT5A Protein Mammalian Cell His
Rat WNT5A-6256R Recombinant Rat WNT5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat WNT5A-6256R-B Recombinant Rat WNT5A Protein Pre-coupled Magnetic Beads HEK293
Rat Wnt5a-65R Recombinant Rat Wnt5a Protein, His-tagged E.coli His
Human/Mouse WNT5A-58H Active Recombinant Human/Mouse WNT5A Protein CHO
Zebrafish WNT5A-4899Z Recombinant Zebrafish WNT5A Mammalian Cell His
Chicken WNT5A-6450C Recombinant Chicken WNT5A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Wnt5a Related Articles
  • Wnt5a Related Gene Family
  • Wnt5a Related Research Area
  • Wnt5a Related Signal Pathway

Wnt5a involved in several pathways and played different roles in them. We selected most pathways Wnt5a participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Wnt5a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwaySFRP5;PPP3CB;WNT3;NFATC2;FBXW11B;NKD1;SIAH2L;MAPK8;NKD2
Hedgehog signaling pathwayWNT9A;CSNK1A1L;DYRK1A;CSNK1G2A;WNT8B;SKI;WNT2;STK36;WNT16
Hippo signaling pathwayWWTR1;Fzd4;WNT9A;WNT3;TGFB3;PPP2R2A;APC2;MOB1A;WNT4
Signaling pathways regulating pluripotency of stem cellsNANOG;FGFR1;WNT2;PIK3CD;ZIC3;SMAD3;SMAD9;FGFR3;WNT5B
MelanogenesisDVL3A;PLCB1;FZD7;FZD3B;PRKCA;WNT5A;WNT4A;CAMK2D1;CALML5
HTLV-I infectionWNT5B;KAT2B;AKT2;VCAM1;PRKACB;ICAM1;EGR1;TRP53;PPP3R1
Pathways in cancerFADD;STAT5A;CBLB;RASSF1;SOS1;FGF9;BID;PML;CCNE2
Proteoglycans in cancerCOL21A1;PTCH1;ERBB4;TWIST2;Casp3;HOXD10;PLCE1;VEGFA;PTK2
Basal cell carcinomaAPC2;TRP53;STK36;BMP4;TCF7L2;FZD2;GLI2;WNT8A;GSK3B

Wnt5a has several biochemical functions, for example, cytokine activity, frizzled binding, frizzled-2 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Wnt5a itself. We selected most functions Wnt5a had, and list some proteins which have the same functions with Wnt5a. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCD70;THPO;BMP3;TNFSF18;Ifnl2;CSF1;RNF207B;SECTM1;IFNL3
frizzled bindingWNT7B;WNT5B;LRP6;WNT6;FZD7;WNT9B;DVL3;WNT11R;WNT8A
frizzled-2 bindingWNT5A;WNT3A
protein domain specific bindingIRS2;TH;RCC2;HGS;YWHAG;TRP63;ODF1;DDC;HIST1H4J
receptor agonist activityWNT8A;VEGFA;NODAL;WNT5A;WNT7A;WNT10B;WNT4;WNT2;GAS6
receptor tyrosine kinase-like orphan receptor binding
transcription factor activity, sequence-specific DNA bindingNANOG;SOX1;CSRNP2;STAT1A;ZKSCAN1;FOSL1;DBPB;ZFP191;ZNF615
transcription regulatory region DNA bindingRBBP5;ZFP382;PPARG;ZNF174;RFX3;CARM1;LEF1;SFPQ;IKZF3

Wnt5a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Wnt5a here. Most of them are supplied by our site. Hope this information will be useful for your research of Wnt5a.

FZD5

Shojima, K; Sato, A; et al. Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively. SCIENTIFIC REPORTS 5:-(2015).
Kikuchi, R; Nakamura, K; et al. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. NATURE MEDICINE 20:1464-1471(2014).
WNT
  • Q&As
  • Reviews

Q&As (7)

Ask a question
What role does WNT5A play in cancer biology? 09/05/2022

Its role in cancer is complex, acting as a tumor suppressor or promoter depending on context.

How does WNT5A interact with its receptors to initiate signal transduction? 04/24/2022

It binds to Frizzled receptors and co-receptors, activating non-canonical Wnt signaling pathways.

In which developmental processes is WNT5A critically involved? 03/14/2022

WNT5A is involved in embryonic development, particularly in limb formation and organogenesis.

How is WNT5A implicated in immune system regulation? 01/03/2022

WNT5A modulates various immune responses, influencing inflammation and cell migration.

What is the primary role of WNT5A in cellular processes? 10/29/2020

WNT5A is crucial in regulating cell proliferation, migration, and differentiation.

What therapeutic strategies are being explored involving WNT5A modulation? 11/14/2019

Strategies include developing WNT5A modulators for potential use in cancer therapy and regenerative medicine.

Are there known genetic mutations in WNT5A associated with specific diseases? 02/27/2019

Genetic mutations and altered expression of WNT5A are linked to developmental disorders and cancer.

Customer Reviews (3)

Write a review
Reviews
11/14/2019

    Satisfied with performance, quality.

    08/27/2019

      Great product, satisfied customer.

      02/27/2019

        High purity, works well.

        Ask a Question for All Wnt5a Products

        Required fields are marked with *

        My Review for All Wnt5a Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends