Wnt5a Protein, wingless-type MMTV integration site family, member 5A

Wnt5a

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Wnt5a

Official Full Name wingless-type MMTV integration site family, member 5A
Background The Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transm
Synonyms WNT5A; wingless-type MMTV integration site family, member 5A; protein Wnt-5a; hWNT5A; WNT 5A protein; WNT-5A protein
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • L-Wnt-5a-expressing Mouse Fibroblast
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WNT5A-11H Recombinant Human/Mouse Wnt-5a Protein, Biotinylated CHO
    Human WNT5A-2474H Recombinant Human WNT5A Protein (62-380 aa), His-tagged Yeast His
    Human WNT5A-1634H Recombinant Human WNT5A protein, His-tagged E.coli His
    Human WNT5A-19H Recombinant Human WNT5A protein CHO N/A
    Human WNT5A-2052H Recombinant Human WNT5A, GST-tagged Wheat Germ GST
    Human WNT5A-2053H Recombinant Human WNT5A, MYC/DDK-tagged HEK293 Myc/DDK
    Human WNT5A-2055H Recombinant Human WNT5A, GST-tagged Wheat Germ GST
    Human WNT5A-206H Recombinant Human WNT5A, StrepII-tagged Human Cell Strep II
    Human WNT5A-20H Recombinant Human WNT5A Protein, GST-tagged E.coli GST
    Human WNT5A-293HCL Recombinant Human WNT5A 293 Cell Lysate HEK293 N/A
    Mouse Wnt5a-1492M Recombinant Mouse Wnt5a protein, GST-tagged E.coli GST
    Mouse WNT5A-18573M Recombinant Mouse WNT5A Protein Mammalian Cell His
    Mouse Wnt5a-2051M Recombinant Mouse Wingless-Related MMTV Integration Site 5A L-Wnt-5a-expressing Mouse Fibroblast N/A
    Mouse Wnt5a-2054M Recombinant Mouse Wnt5a CHO N/A
    Mouse Wnt5a-2055M Recombinant Mouse Wnt5a protein, His/GST-tagged E.coli His/GST
    Rat Wnt5a-65R Recombinant Rat Wnt5a Protein, His-tagged E.coli His
    Rat WNT5A-6600R Recombinant Rat WNT5A Protein Mammalian Cell His
    Chicken WNT5A-6450C Recombinant Chicken WNT5A Mammalian Cell His
    Zebrafish WNT5A-4899Z Recombinant Zebrafish WNT5A Mammalian Cell His

    Wnt5a involved in several pathways and played different roles in them. We selected most pathways Wnt5a participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Wnt5a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway WNT8B; SIAH1A; SFRP1A; PRKCBA; CCND3; CACYBP; DVL3A; TBL1Y; RHOAC; NKD2
    Hedgehog signaling pathway GLI2B; ZIC2A; HHIP; FBXW11; WNT5B; CSNK1A1L; SKI; SMO; FBXW11B; DYRK1A
    Hippo signaling pathway ID1; FZD5; INADL; BIRC2; BMP4; PPP2CB; SMAD7; TEAD1; AXIN1; TCF7
    Signaling pathways regulating pluripotency of stem cells HRAS; MAPK1; FZD2; SMAD1; WNT2B; AKT2; ACVR1; WNT8A; MAPK12; ACVR1C
    Melanogenesis WNT7B; FZD3; EDNRBA; FZD7B; WNT2; GNAI3; WNT8A; WNT7AA; KITLGA; PLCB1
    HTLV-I infection POLE2; FZD9; TGFBR2; NFYB; RRAS; PPP3CA; CANX; CD40; ATF4; GM-CSF
    Pathways in cancer LAMA5; BDKRB2; CUL2; LAMA2; FGF20; TRAF5; BIRC7; FZD3; RALBP1; FZD9
    Proteoglycans in cancer RAC1; TRP53; ANK1; CAV1; Casp3; FGFR1; FLNC; WNT5B; FGF2; WNT10B
    Basal cell carcinoma WNT3; WNT7B; GSK3B; FZD6; GLI2; SUFU; FZD7; BMP4; WNT2; WNT1

    Wnt5a has several biochemical functions, for example, cytokine activity, frizzled binding, frizzled-2 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Wnt5a itself. We selected most functions Wnt5a had, and list some proteins which have the same functions with Wnt5a. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity BMP10; GREM2; TSLP; IFNA1; CCL38A.4; SECTM1; GDF10; LTB; CLCF1; OSM
    frizzled binding WNT10B; RNF43; WNT7AA; WNT2BA; WNT8A; WNT9A; WNT4; SDCBP; WNT1; WNT4B
    frizzled-2 binding WNT5A; WNT3A
    protein domain specific binding RAP2B; TWIST2; RXRA; VCP; IL1B; IST1; TADA3; FOXA2; CHMP1B; IKBKG
    receptor agonist activity WNT1; WNT8A; WNT3; WNT10B; GAS6; WNT4; WNT5A; WNT3A; NODAL; WNT7A
    receptor tyrosine kinase-like orphan receptor binding WNT5A
    transcription factor activity, sequence-specific DNA binding SOX9; ETV6; HMGB1; ZNF792; ZHX1; HNF1BB; CLOCK; FOXF2; SOX6; ZNF26
    transcription regulatory region DNA binding ATF3; MZF1; RREB1; GRHL2B; NR1D1; MTERF3; SOX6; TBL1XR1; KCNA3; PHB

    Wnt5a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Wnt5a here. Most of them are supplied by our site. Hope this information will be useful for your research of Wnt5a.

    FZD5

    Shojima, K; Sato, A; et al. Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively. SCIENTIFIC REPORTS 5:-(2015).
    Kikuchi, R; Nakamura, K; et al. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. NATURE MEDICINE 20:1464-1471(2014).

    WNT

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