Recombinant Human CCL20, His-tagged CCL20-166H

Recombinant Human CCL20, His-tagged


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Recombinant Human CCL20, His-tagged

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Cat.No. : CCL20-166H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human CCL20 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Description : CCL20, also known as Macrophage Inflammatory Protein-3 (MIP3A), is a small cytokine belonging to the CC chemokine family. CCL20 protein is strongly chemotactic for lymphocytes and weakly attracts neutrophils. It is implicated in the formation and function of mucosal lymphoid tissues via chemoattraction of lymphocytes and dendritic cells towards the epithelial cells surrounding these tissues.
Source : E.coli.
Form : Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
Molecular Weight : 10.3 kDa (91aa) confirmed by MALDI-TOF.
Purity : > 85% by SDS - PAGE.
Concentration : 0.25 mg/ml (determined by Bradford assay).
Endotoxin Level : < 1.0 EU per 1 μg of protein (determined by LAL method).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Chemokine signaling pathway; Cytokine-cytokine receptor interaction
PDBrendering based on 1m8a. :

Gene Name : CCL20 chemokine (C-C motif) ligand 20 [ Homo sapiens ]
Synonyms : CCL20; chemokine (C-C motif) ligand 20; CKb4; LARC; MIP-3-alpha; MIP-3a; MIP-3[a]; MIP3A; SCYA20; ST38; exodus-1; Exodus-1; Beta chemokine exodus-1; CC chemokine LARC; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; Small-inducible cytokine A20; Small inducible cytokine subfamily A (Cys-Cys), member 20; Small inducible cytokine A20 precursor; C-C motif chemokine 20; CC chemokine ST38; OTTMUSP00000017965; Small inducible cytokine subfamily A20
Gene ID : 6364
mRNA Refseq : NM_004591
Protein Refseq : NP_004582
MIM : 601960
UniProt ID : P78556
Chromosome Location : 2q33-q37
Function : chemokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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