Active Recombinant Human CCL20 Protein, HIgG1 Fc-tagged, mutant

Cat.No. : CCL20-515H
Product Overview : The extracellular domain of human CCL20 (AAH20698.1)(Ala27-Met96) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
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Source : CHO
Species : Human
Tag : HIgG1 Fc
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to chemoattract BaF3 mouse pro-B cells.
Molecular Mass : 34KDa (monomer)
Endotoxin : 0.06 eu/μg as determined by lal test.
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Gene Name : CCL20 chemokine (C-C motif) ligand 20 [ Homo sapiens ]
Official Symbol : CCL20
Synonyms : CCL20; chemokine (C-C motif) ligand 20; SCYA20, small inducible cytokine subfamily A (Cys Cys), member 20; C-C motif chemokine 20; CKb4; exodus 1; LARC; MIP 3a; ST38; exodus-1; MIP-3-alpha; CC chemokine LARC; beta chemokine exodus-1; beta-chemokine exodus-1; small-inducible cytokine A20; macrophage inflammatory protein 3 alpha; liver and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 20; MIP3A; MIP-3a; SCYA20;
Gene ID : 6364
mRNA Refseq : NM_001130046
Protein Refseq : NP_001123518
MIM : 601960
UniProt ID : P78556

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What are the mechanisms by which CCL20 modulates the migration and differentiation of dendritic cells? 08/25/2022

CCL20 influences dendritic cell migration and differentiation, crucial for initiating immune responses.

How does CCL20 contribute to tumor progression and the formation of the tumor microenvironment in cancer? 07/07/2022

CCL20 contributes to cancer progression by shaping the tumor microenvironment and aiding tumor cell invasion.

What role does CCL20 play in the pathogenesis of autoimmune diseases like rheumatoid arthritis? 05/17/2022

CCL20 plays a significant role in autoimmune diseases by attracting inflammatory cells to affected joints.

How does CCL20 influence wound healing and tissue repair processes? 12/21/2021

CCL20 is involved in wound healing and tissue repair, facilitating immune cell migration and tissue regeneration.

How do alterations in CCL20 expression or signaling affect skin homeostasis and the development of skin diseases? 09/05/2021

Changes in CCL20 expression impact skin health, potentially contributing to the development of skin disorders.

How does CCL20 mediate the recruitment and activation of immune cells, particularly in inflammatory conditions? 08/22/2020

CCL20 recruits and activates immune cells to sites of inflammation, coordinating the immune response.

What is the impact of CCL20 on mucosal immunity, especially in the gut and respiratory tract? 08/06/2019

CCL20 impacts mucosal immunity, playing a critical role in immune defense in the gut and respiratory system.

Customer Reviews (3)

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Reviews
08/25/2020

    Expert protein engineering support, essential for our projects' progress.

    05/14/2020

      Consistent western blot results, an indispensable tool in our lab.

      08/22/2019

        Dependable protein quantification, ensures data precision in our work.

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