Recombinant Mouse CCL20 Protein (Ala28-Met97)
Cat.No. : | CCL20-793M |
Product Overview : | Recombinant Mouse CCL20 Protein (NP_058656.1) (Ala28-Met97) was produced by E. coli expression system. This protein was expressed with an initial Met. |
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Description : | Chemokine (C-C motif) ligand 2 (CCL2) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL2 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL2 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL2 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL2 was shown to play a role in colorectal cancer (CRC) pathogenesis. |
Source : | E. coli |
Species : | Mouse |
Predicted N Terminal : | Met |
Form : | Lyophilized from sterile PBS. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant mouse CCL20 consists of 71 amino acids and predicts a molecular mass of 8.1 kDa. |
Protein length : | Ala28-Met97 |
Purity : | > 95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Shipping : | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Tag : | Non |
Gene Name : | Ccl20 chemokine (C-C motif) ligand 20 [ Mus musculus ] |
Official Symbol : | CCL20 |
Synonyms : | CCL20; MIP-3-alpha; CC chemokine LARC; CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1; |
Gene ID : | 20297 |
mRNA Refseq : | NM_001159738 |
Protein Refseq : | NP_001153210 |
UniProt ID : | O89093 |
Products Types
◆ Recombinant Protein | ||
CCL20-515H | Active Recombinant Human CCL20 Protein, HIgG1 Fc-tagged, mutant | +Inquiry |
CCL20-218C | Active Recombinant Human CCL20 Protein (70 aa) | +Inquiry |
CCL20-3403M | Recombinant Mouse CCL20 protein(Ala28-Met97) | +Inquiry |
CCL20-073C | Active Recombinant Human CCL20 Protein (70 aa) | +Inquiry |
CCL20-870R | Recombinant Rat CCL20 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewExpert protein engineering support, essential for our projects' progress.
Consistent western blot results, an indispensable tool in our lab.
Dependable protein quantification, ensures data precision in our work.
Q&As (7)
Ask a questionCCL20 influences dendritic cell migration and differentiation, crucial for initiating immune responses.
CCL20 contributes to cancer progression by shaping the tumor microenvironment and aiding tumor cell invasion.
CCL20 plays a significant role in autoimmune diseases by attracting inflammatory cells to affected joints.
CCL20 is involved in wound healing and tissue repair, facilitating immune cell migration and tissue regeneration.
Changes in CCL20 expression impact skin health, potentially contributing to the development of skin disorders.
CCL20 recruits and activates immune cells to sites of inflammation, coordinating the immune response.
CCL20 impacts mucosal immunity, playing a critical role in immune defense in the gut and respiratory system.
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