• Official Full Name

    chemokine (C-C motif) ligand 8

  • Background

    Monocyte chemotactic protein-2 (MCP-2); is a non-glycosylated polypeptide that is a member of the C-C chemokine subfamily and it specifically attracts monocytes, lymphocytes, basophils and eosinophils. It also plays a role in neoplasia and inflammatory ho
  • Synonyms

    CCL8; chemokine (C-C motif) ligand 8; SCYA8, small inducible cytokine subfamily A (Cys Cys), member 8 (monocyte chemotactic protein 2); C-C motif chemokine 8; HC14; MCP 2; small-inducible cytokine A8; monocyte chemotactic protein 2; monocyte chemoattract;
    • Type:
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Canine
    • Cattle
    • Dog
    • Horse
    • Human
    • Mouse
    • Pig
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293F
    • Human Cells
    • Mammalian Cell
    • Mammalian cells
    • Yeast
    • Tag :
    • C
    • His
    • DDK
    • Fc
    • GST
    • His (Fc)
    • Avi
    • His|GST
    • His|NusA
    • His|T7
    • N/A
    • N
    • SUMO
    • Tag Free
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Canine CCL8-29C Recombinant Canine CCL8 protein E.coli N/A
    Cattle CCL8-692C Recombinant Cattle CCL8 protein, His & GST-tagged E.coli His/GST
    Dog CCL8-2734D Recombinant Dog CCL8 Protein, His-tagged HEK293F N-His
    Horse CCL8-1105H Recombinant Horse CCL8 Protein, His-tagged E.coli N-His
    Human CCL8-28723TH Recombinant Human CCL8 E.coli N/A
    Human CCL8-198H Recombinant Human CCL8, SUMO tagged E.coli SUMO
    Human CCL8-45H Recombinant Human CCL8 Protein E.coli
    Human CCL8-284H Recombinant Human CCL8 protein E.coli N/A
    Human CCL8-302H Active Recombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged, mutant CHO Fc
    Human CCL8-304H Active Recombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged CHO Fc
    Human CCL8-079C Recombinant Human CCL8 Protein (76 aa) E.coli
    Human CCL8-031H Recombinant Human CCL8 Protein, His-tagged HEK293 His
    Human CCL8-34H Recombinant Human CCL8 Protein E.coli
    Human CCL8-303H Active Recombinant Human Chemokine (C-C Motif) Ligand 8, MIgG2a Fc-tagged CHO Fc
    Human CCL8-30121H Recombinant Human CCL8 protein, GST-tagged E.coli GST
    Human CCL8-693H Recombinant Human CCL8 protein, His & T7-tagged E.coli His/T7
    Human CCL8-1267H Recombinant Human CCL8 Protein (Gln24-Pro99) E.coli Tag Free
    Human CCL8-313H Recombinant Human CCL8 Protein, His-tagged Yeast His
    Human CCL8-1290H Recombinant Human CCL8 Protein (Ser29-Pro99), N-His tagged E.coli N-His
    Human CCL8-336C Recombinant Human CCL8 Protein (76 aa) E.coli
    Human CCL8-032H Recombinant Human CCL8 Protein, DDK-tagged HEK293 DDK
    Human CCL8-151H Recombinant Human CCL8 Protein, His-tagged Human Cells His
    Human CCL8-1266H Recombinant Human CCL8 Protein (Gln24-Pro99), C-His tagged Mammalian cells C-His
    Human CCL8-2656H Recombinant Human CCL8 protein, GST-tagged E.coli GST
    Human CCL8-37H Recombinant Human CCL8 protein, His-tagged E.coli His
    Mouse CCL8-35M Recombinant Mouse CCL8 Protein E.coli
    Mouse Ccl8-694M Recombinant Mouse Ccl8 protein, His & T7-tagged E.coli His/T7
    Mouse Ccl8-202M Recombinant Mouse Ccl8, His & NusA tagged E.coli His/NusA
    Mouse Ccl8-2042M Recombinant Mouse Ccl8 Protein E. coli
    Mouse Ccl8-285M Active Recombinant Mouse Chemokine (C-C Motif) Ligand 8 E.coli N/A
    Mouse Ccl8-021C Recombinant Mouse Ccl8 Protein (74 aa) E.coli
    Mouse Ccl8-003M Recombinant Mouse Ccl8 Protein E.coli
    Mouse Ccl8-10854m Recombinant mouse Ccl8, GST-tagged E.coli GST
    Mouse Ccl8-100M Recombinant Mouse Ccl8 protein E.coli N/A
    Pig CCL8-695P Recombinant Pig CCL8 protein, His & GST-tagged E.coli His/GST
    Rhesus Macaque CCL8-522R Recombinant Rhesus Macaque CCL8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque CCL8-694R Recombinant Rhesus monkey CCL8 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CCL8-522R-B Recombinant Rhesus Macaque CCL8 Protein Pre-coupled Magnetic Beads HEK293
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • CCL8 Related Articles
    • CCL8 Related Gene Family
    • CCL8 Related Research Area

    CCL8 involved in several pathways and played different roles in them. We selected most pathways CCL8 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionEPO;Fasl;TNFRSF8;IL18R1;NGFRB;CCL8;XCL2;IFNA12;VEGFAA
    Chemokine signaling pathwayCcl9;CCL8;CCL20;GNB4;CXCL3;PIK3R3;MAP2K1;CX3CR1;PF4

    CCL8 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL8 itself. We selected most functions CCL8 had, and list some proteins which have the same functions with CCL8. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor bindingCCL3L3;XCL2;CCL18;CCL17;CCL38A.4;CCL35.1;CCL26;CCL20;CCL38A.5
    chemokine activityCXCL12A;CCL15;CXCL11.8;CCL27;CCL35.2;CCL19A.2;CCL34B.1;CCL38A.5;CCL4
    heparin bindingFGF14;HRG;ABP1;FGF9;FGF10;PTPRF;CXCL13;HDGF;SELL
    phospholipase activator activityCCL3;CCL8;GM2A;ARHGAP6;PDPK1;CCL5;APOC2
    protein kinase activityACVR2AA;SGK196;EPHA4A;PRKCI;AVP;TNK2B;NEK2;TGFBR1;MKNK2B

    CCL8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL8.

    Hayes, LN; Severance, EG; et al. Inflammatory Molecular Signature Associated With Infectious Agents in Psychosis. SCHIZOPHRENIA BULLETIN 40:963-972(2014).
    Ludlow, LE; Hasang, W; et al. Peripheral Blood Mononuclear Cells Derived from Grand Multigravidae Display a Distinct Cytokine Profile in Response to P. falciparum Infected Erythrocytes. PLOS ONE 9:-(2014).
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