ccl8

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ccl8

Official Full Name chemokine (C-C motif) ligand 8
Background Monocyte chemotactic protein-2 (MCP-2); is a non-glycosylated polypeptide that is a member of the C-C chemokine subfamily and it specifically attracts monocytes, lymphocytes, basophils and eosinophils. It also plays a role in neoplasia and inflammatory ho
Synonyms CCL8; chemokine (C-C motif) ligand 8; SCYA8, small inducible cytokine subfamily A (Cys Cys), member 8 (monocyte chemotactic protein 2); C-C motif chemokine 8; HC14; MCP 2; small-inducible cytokine A8; monocyte chemotactic protein 2; monocyte chemoattract
    • Species :
    • Canine
    • Cattle
    • Human
    • Mouse
    • Pig
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • Human Cells
    • Mammalian Cell
    • Yeast
    • Tag :
    • DDK
    • Fc
    • GST
    • His
    • NusA
    • T7
    • N/A
    • SUMO
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL8-151H Recombinant Human CCL8 Protein, His-tagged Human Cells His
    Human CCL8-031H Recombinant Human CCL8 Protein, His-tagged HEK293 His
    Human CCL8-032H Recombinant Human CCL8 Protein, DDK-tagged HEK293 DDK
    Human CCL8-198H Recombinant Human CCL8, SUMO tagged E.coli SUMO
    Human CCL8-284H Recombinant Human CCL8 protein E.coli N/A
    Human CCL8-28723TH Recombinant Human CCL8 E.coli N/A
    Human CCL8-302H Recombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged, mutant CHO Fc
    Human CCL8-303H Recombinant Human Chemokine (C-C Motif) Ligand 8, MIgG2a Fc-tagged CHO Fc
    Human CCL8-304H Recombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged CHO Fc
    Human CCL8-313H Recombinant Human CCL8 Protein, His-tagged Yeast His
    Human CCL8-693H Recombinant Human CCL8 protein, His & T7-tagged E.coli His/T7
    Mouse Ccl8-003M Recombinant Mouse Ccl8 Protein E.coli
    Mouse Ccl8-100M Recombinant Mouse Ccl8 protein E.coli N/A
    Mouse Ccl8-10854m Recombinant mouse Ccl8, GST-tagged E.coli GST
    Mouse Ccl8-202M Recombinant Mouse Ccl8, His & NusA tagged E.coli His/NusA
    Mouse Ccl8-2042M Recombinant Mouse Ccl8 Protein E. coli
    Mouse Ccl8-285M Recombinant Mouse Chemokine (C-C Motif) Ligand 8 E.coli N/A
    Mouse Ccl8-694M Recombinant Mouse Ccl8 protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque CCL8-694R Recombinant Rhesus monkey CCL8 Protein, His-tagged Mammalian Cell His
    Canine CCL8-29C Recombinant Canine CCL8 protein E.coli N/A
    Cattle CCL8-692C Recombinant Cattle CCL8 protein, His & GST-tagged E.coli His/GST
    Pig CCL8-695P Recombinant Pig CCL8 protein, His & GST-tagged E.coli His/GST

    ccl8 involved in several pathways and played different roles in them. We selected most pathways ccl8 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ccl8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL1R2; IFNA7; TNFSF14; Flt3l; CX3CR1; IL3; IL18RAP; TNFRSF25; CCL17; CCR6
    Chemokine signaling pathway GNAI2; GNB3; PIK3CG; CXCL12; GNG12; CCL1; RHOA; GNG5; SHC1; LYN

    ccl8 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ccl8 itself. We selected most functions ccl8 had, and list some proteins which have the same functions with ccl8. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor binding CCL14; CCL11; CCRL2; CCL20A.3; CCL26; XCL2; CCL19A.1; CCL19; CCL19B; CCL20B
    chemokine activity CCL7; CCL23; CCL21B; CKLF; Ccl21c; IL-8; Ccl12; CCL21; CXCL2; CCL1
    heparin binding LIPI; RSPO3; GM4980; RSPO4; APPA; APLP1; COL13A1; COL25A1; APOH; REG4
    phospholipase activator activity GM2A; PDPK1; APOC2; CCL3; CCL5; CCL8; ARHGAP6
    protein kinase activity TEX14; CSNK2A2A; PDPK1A; PTK2AA; EPHA4; PTK2AB; CSNK1A1; TNIKB; AKT1; CDK9

    ccl8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ccl8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ccl8.

    Hayes, LN; Severance, EG; et al. Inflammatory Molecular Signature Associated With Infectious Agents in Psychosis. SCHIZOPHRENIA BULLETIN 40:963-972(2014).
    Ludlow, LE; Hasang, W; et al. Peripheral Blood Mononuclear Cells Derived from Grand Multigravidae Display a Distinct Cytokine Profile in Response to P. falciparum Infected Erythrocytes. PLOS ONE 9:-(2014).

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