CCL8

  • Official Full Name

    chemokine (C-C motif) ligand 8

  • Overview

    Monocyte chemotactic protein-2 (MCP-2); is a non-glycosylated polypeptide that is a member of the C-C chemokine subfamily and it specifically attracts monocytes, lymphocytes, basophils and eosinophils. It also plays a role in neoplasia and inflammatory ho
  • Synonyms

    CCL8; chemokine (C-C motif) ligand 8; SCYA8, small inducible cytokine subfamily A (Cys Cys), member 8 (monocyte chemotactic protein 2); C-C motif chemokine 8; HC14; MCP 2; small-inducible cytokine A8; monocyte chemotactic protein 2; monocyte chemoattract;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Cattle
  • Dog
  • Horse
  • Human
  • Mouse
  • Pig
  • Rhesus Macaque
  • CHO
  • E.coli
  • HEK293
  • HEK293F
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • C
  • His
  • DDK
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • N/A
  • N
  • NusA
  • SUMO
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCL8-302H Active Recombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged, mutant CHO Fc
Human CCL8-304H Active Recombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged CHO Fc
Human CCL8-303H Active Recombinant Human Chemokine (C-C Motif) Ligand 8, MIgG2a Fc-tagged CHO Fc
Human CCL8-079C Active Recombinant Human CCL8 Protein (76 aa) E.coli 76
Human CCL8-284H Recombinant Human CCL8 protein E.coli N/A 76
Human CCL8-032H Recombinant Human CCL8 Protein, DDK-tagged HEK293 DDK
Human CCL8-198H Recombinant Human CCL8, SUMO tagged E.coli SUMO
Human CCL8-28723TH Recombinant Human CCL8 E.coli N/A
Human CCL8-693H Recombinant Human CCL8 protein, His & T7-tagged E.coli His/T7 Met1~Pro99 (Accession # P80075)
Human CCL8-031H Recombinant Human CCL8 Protein, His-tagged HEK293 His
Human CCL8-45H Recombinant Human CCL8 Protein E.coli 76 AA
Human CCL8-313H Recombinant Human CCL8 Protein, His-tagged Yeast His Gln24-Pro99
Human CCL8-34H Recombinant Human CCL8 Protein E.coli
Human CCL8-336C Active Recombinant Human CCL8 Protein (76 aa) E.coli 76
Human CCL8-30121H Recombinant Human CCL8 protein, GST-tagged E.coli GST Pro22-99Pro
Human CCL8-151H Recombinant Human CCL8 Protein, His-tagged Human Cells His
Human CCL8-1267H Recombinant Human CCL8 Protein (Gln24-Pro99) E.coli Tag Free Gln24-Pro99
Human CCL8-1266H Recombinant Human CCL8 Protein (Gln24-Pro99), C-His tagged Mammalian cells C-His Gln24-Pro99
Human CCL8-1290H Recombinant Human CCL8 Protein (Ser29-Pro99), N-His tagged E.coli N-His Ser29-Pro99
Human CCL8-2656H Recombinant Human CCL8 protein, GST-tagged E.coli GST 24-99aa
Human CCL8-37H Recombinant Human CCL8 protein, His-tagged E.coli His
Mouse Ccl8-285M Active Recombinant Mouse Chemokine (C-C Motif) Ligand 8 E.coli N/A
Mouse Ccl8-021C Active Recombinant Mouse Ccl8 Protein (74 aa) E.coli 74
Mouse Ccl8-003M Active Recombinant Mouse Ccl8 Protein E.coli
Mouse Ccl8-2042M Active Recombinant Mouse Ccl8 Protein E.coli Gly24-Pro97
Mouse Ccl8-100M Recombinant Mouse Ccl8 protein E.coli N/A 74
Mouse Ccl8-694M Recombinant Mouse Ccl8 protein, His & T7-tagged E.coli His/T7 Glu20~Ile94 (Accession # Q9Z121)
Mouse Ccl8-202M Recombinant Mouse Ccl8 protein(Gly24-Pro94), His&NusA-tagged E.coli N-His&NusA Gly24-Pro94
Mouse Ccl8-10854m Recombinant mouse Ccl8, GST-tagged E.coli GST 11-97a.a.
Mouse CCL8-35M Recombinant Mouse CCL8 Protein E.coli
Mouse Ccl8-5744M Recombinant Mouse Ccl8 Protein (Glu20-Pro97), C-His tagged Mammalian cells C-His Glu20-Pro97
Dog CCL8-2734D Recombinant Dog CCL8 Protein, His-tagged HEK293F N-His Gln24-Pro99
Canine CCL8-29C Recombinant Canine CCL8 protein E.coli N/A 76
Cattle CCL8-692C Recombinant Cattle CCL8 protein, His & GST-tagged E.coli His/GST Met1~Pro99 (Accession # Q09141)
Horse CCL8-1105H Recombinant Horse CCL8 Protein, His-tagged E.coli N-His Gln24-Pro99
Rhesus Macaque CCL8-694R Recombinant Rhesus monkey CCL8 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCL8-522R Recombinant Rhesus Macaque CCL8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CCL8-522R-B Recombinant Rhesus Macaque CCL8 Protein Pre-coupled Magnetic Beads HEK293
Pig CCL8-695P Recombinant Pig CCL8 protein, His & GST-tagged E.coli His/GST Gln24~Pro99 (Accession # P49873)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CCL8 involved in several pathways and played different roles in them. We selected most pathways CCL8 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionBMP7A;Il6ra;PRLRA;TNFRSF13B;IL2RG;TNFRSF18;EDAR;VEGFAA;IL18RAP
Chemokine signaling pathwayGSK3B;AKT2;GNG5;GNAI1;GNG2;CXCL9;CXCL11;CXCL13;CCR1L1

CCL8 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL8 itself. We selected most functions CCL8 had, and list some proteins which have the same functions with CCL8. You can find most of the proteins on our site.

Function Related Protein
CCR chemokine receptor bindingCCL20B;CCL24;CCL17;CCL20;CCL22;CCL34B.1;CCL26;CCL38.1;CCRL2
chemokine activityCcl9;CCL6;CCL34B.9;CCL11;CCL33.3;CCL24;CCL35.1;CCL4;AMCF-II
heparin bindingFGFBP1;ITGAM;FGFR2;ADAMTS1;NELL2;Epy;BMP4;NRP1A;SFRP1
phospholipase activator activityCCL5;CCL8;PDPK1;APOC2;ARHGAP6;CCL3;GM2A
protein kinase activityRLN1;MAP4K6;JAK2B;PRPF4BB;STK17B;MAP4K1;GSG2;BMPR1BB;SGK2B

CCL8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL8.

Gene Family

Chemokines Cytokines

Research Area

Related articles

Hayes, LN; Severance, EG; et al. Inflammatory Molecular Signature Associated With Infectious Agents in Psychosis. SCHIZOPHRENIA BULLETIN 40:963-972(2014).
Ludlow, LE; Hasang, W; et al. Peripheral Blood Mononuclear Cells Derived from Grand Multigravidae Display a Distinct Cytokine Profile in Response to P. falciparum Infected Erythrocytes. PLOS ONE 9:-(2014).
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