|Official Full Name||CD36 molecule (thrombospondin receptor)|
|Background||The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]|
|Synonyms||CD36; CD36 molecule (thrombospondin receptor); FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; platelet glycoprotein 4; GPIIIB; PAS IV; PAS-4 protein; glycoprotein IIIb; cluster determinant 36; fatty acid translocase; platelet glycoprotein IV; scavenger receptor class B, member 3; leukocyte differentiation antigen CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cd36 involved in several pathways and played different roles in them. We selected most pathways cd36 participated on our site, such as PPAR signaling pathway, Phagosome, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|PPAR signaling pathway||ACAA1; CYP4A14; ACOX3; FABP5; MMP1A; ACSL4; PPARA; ACOX1; PDPK1B; RXRA|
|Phagosome||NOX1; TUBA3B; THBS4A; FCGR2A; HLA-G; HLA-DQA1; SEC61G; FAM49BA; DYNC1LI1; CTSLA|
|AMPK signaling pathway||AKT3; PPP2R1A; TSC2; LIPE; FASN; PIK3R5; CREB3L3; SLC2A4; LEPR; CFTR|
|ECM-receptor interaction||COL1A1A; COL4A2; COL4A1; COL27A1B; SDC4; THBS4A; GP1BA; GP9; ITGA4; LAMA4|
|Hematopoietic cell lineage||CD36; GP1BB; IL11RA; THPO; CD1A; CD1D; MS4A1; Fcer2a; Flt3l; Itgam&Itgb2|
|Adipocytokine signaling pathway||RXRG; ACSL3A; ADIPOR1; NFKBIE; POMC; STK11; POMCA; SLC2A1A; CHUK; PRKAB1|
|Insulin resistance||AKT2; PPP1R3C; IRS2; PRKCBA; PRKAB1B; FOXO1A; PPP1CAA; IKBKB; RPS6KA1; PIK3CA|
|Fat digestion and absorption||SCARB1; PPAP2A; LIPF; PLA2G1B; AGPAT1; APOA1; MOGAT2; GOT2; FABP1; PLA2G12B|
|Malaria||Ccl12; THBS1; HBA1; IL-8; CD40LG; GYPC; SDC1; SELE; MET; HBB-B2|
cd36 has several biochemical functions, for example, MAP-kinase scaffold activity, kinesin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd36 itself. We selected most functions cd36 had, and list some proteins which have the same functions with cd36. You can find most of the proteins on our site.
|MAP-kinase scaffold activity||CD36; MAPK8IP3; DUSP19; JIP1; MAPK8IP2; SPAG9; KSR1; SPAG9A|
|kinesin binding||DISC1; CD36; KIAA1279; SNCA; ACTB; PIFO; MAPK8IP3; KIF1B; JIP1; KIFAP3|
|protein binding||HMOX1; RNASEL; SMOC1; JUP; TOMM70A; PFKL; PIWIL1; WWOX; PPP1R7; DNMT3B|
|protein kinase binding||GSK3B; CD226; MAP3K12; CAV1; PPP1CB; CACNB2; ERRFI1; ACTA2; RCC2; TRAF4|
|protein kinase inhibitor activity||SOCS1B; SH3BP5B; CHP1; TRIB3; TRIB2; SH3BP5; NPM1; TESC; TRIB1; SOCS3|
cd36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd36 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd36.
dacD; cutA; q7ciq1_yerpe; yapE; icc; CHRD; cona_canen