Cd36

  • Official Full Name

    CD36 molecule (thrombospondin receptor)

  • Overview

    The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
  • Synonyms

    CD36; CD36 molecule (thrombospondin receptor); FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; platelet glycoprotein 4; GPIIIB; PAS IV; PAS-4 protein; glycoprotein IIIb; cluster determinant 36; fatty acid translocase; platelet glycoprotein IV; scavenger receptor class B, member 3; leukocyte differentiation antigen CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Canine
  • Chicken
  • Cynomolgus
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mesocricetus auratus (Golden hamster)
  • Monkey
  • Mouse
  • Rat
  • Rhesus Macaque
  • Rhesus monkey
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Avi
  • His
  • C
  • hFc
  • Fc
  • Fc|His
  • Flag
  • GST
  • His (Fc)
  • His|T7
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD36-22H Active Recombinant Human CD36 Protein, Fc-tagged Insect Cell Fc
Human CD36-257H Recombinant Human CD36 protein, His-tagged Insect Cell His
Human CD36-27868TH Recombinant Human CD36, His-tagged Wheat Germ His
Human CD36-3184H Recombinant Human CD36 protein(Gly30-Asn439), His-tagged HEK293 C-His
Human CD36-0795H Recombinant Human CD36 Protein, GST-Tagged Wheat Germ GST
Human CD36-179H Recombinant Human CD36 protein, His-tagged HEK293 His
Human CD36-7084H Recombinant Human CD36 protein, His & T7-tagged E.coli His/T7
Human CD36-0794H Recombinant Human CD36 Protein Wheat Germ N/A
Human CD36-2539HCL Recombinant Human CD36 cell lysate Human Cell N/A
Human CD36-1282H Recombinant Human CD36 protein, His-GST-tagged E.coli His
Human CD36-074H Recombinant Human CD36 protein, His-Avi-tagged HEK293 His-Avi
Human CD36-3084H Recombinant Human CD36 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD36-2828H Recombinant Human CD36 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD36-1957H Recombinant Human CD36 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD36-4963H Recombinant Human CD36 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD36-3163H Recombinant Human CD36 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD36-57HF Recombinant Full Length Human CD36 Protein, His-tagged In Vitro Cell Free System His
Human CD36-39HFL Recombinant Full Length Human CD36 Protein, C-Flag-tagged Mammalian cells Flag
Human CD36-3169HF Recombinant Full Length Human CD36 Protein, GST-tagged In Vitro Cell Free System GST
Human CD36-540H-B Recombinant Human CD36 Protein Pre-coupled Magnetic Beads HEK293
Human CD36-3166HF Recombinant Full Length Human CD36 Protein In Vitro Cell Free System
Human CD36-0942H Recombinant Human CD36 Protein (Leu187-Asn428), N-His tagged E.coli N-His
Human CD36-540H Recombinant Human CD36 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD36-2954H Active Recombinant Human CD36 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CD36-153H Recombinant Human CD36 Protein, His-tagged HEK293 His
Human CD36-5346H Recombinant Human CD36 Protein (Gly30-Asn439), C-His tagged Mammalian cells C-His
Human CD36-3077H Active Recombinant Human CD36 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Human CD36-5347H Recombinant Human CD36 Protein (Gln35-Asn439), C-His tagged Mammalian cells C-His
Mouse Cd36-3323M Active Recombinant Mouse Cd36 protein, His-tagged HEK293 His
Mouse Cd36-3322M Recombinant Mouse Cd36, Fc-His tagged Human Cell Fc/His
Mouse Cd36-7085M Recombinant Mouse Cd36 protein, His & T7-tagged E.coli His/T7
Mouse Cd36-365M Recombinant Mouse Cd36 Protein, His-tagged Insect Cell His
Mouse CD36-2400MCL Recombinant Mouse CD36 cell lysate Human Cell N/A
Mouse Cd36-834M Recombinant Mouse Cd36 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Cd36-7170M Recombinant Mouse Cd36 Protein, His-tagged Insect Cell His
Mouse Cd36-3324M Recombinant Mouse Cd36(Gly30Lys439) Protein, C-Avi-6*His-tagged, Biotinylated HEK293 Avi-His
Rat Cd36-8751R Recombinant Rat Cd36 protein(Gly30-Lys439), hFc-tagged HEK293 C-hFc
Rat Cd36-7086R Recombinant Rat Cd36 protein, His & T7-tagged E.coli His/T7
Rat CD36-1236RCL Recombinant Rat CD36 cell lysate Human Cell N/A
Rat Cd36-716R Recombinant Rat Cd36 protein, His-tagged HEK293 His
Monkey CD36-001M Recombinant Monkey CD36 Protein HEK293
Rhesus monkey CD36-737R Recombinant Rhesus monkey CD36 Protein, Fc-tagged HEK293 Fc
Bos taurus (Bovine) RFL32958BF Recombinant Full Length Bovine Platelet Glycoprotein 4(Cd36) Protein, His-Tagged E.coli expression system His
Canine CD36-3075C Recombinant Canine CD36 protein, His-tagged HEK293 His
Cynomolgus CD36-96C Recombinant Cynomolgus CD36, Fc-tagged HEK293 Fc
Cynomolgus CD36-3076C Recombinant Cynomolgus CD36 protein, His-tagged HEK293 His
Cynomolgus Monkey CD36-1109CCL Recombinant Cynomolgus CD36 cell lysate Human Cell N/A
Homo sapiens (Human) RFL20295HF Recombinant Full Length Human Platelet Glycoprotein 4(Cd36) Protein, His-Tagged E.coli expression system His
Mesocricetus auratus (Golden hamster) RFL4071MF Recombinant Full Length Mesocricetus Auratus Platelet Glycoprotein 4(Cd36) Protein, His-Tagged E.coli expression system His
Rhesus Macaque CD36-736R Recombinant Rhesus monkey CD36 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD36-562R Recombinant Rhesus Macaque CD36 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CD36-562R-B Recombinant Rhesus Macaque CD36 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CD36-508Z Recombinant Zebrafish CD36 Mammalian Cell His
Chicken CD36-2432C Recombinant Chicken CD36 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cd36 Related Articles
  • Cd36 Related Research Area

Cd36 involved in several pathways and played different roles in them. We selected most pathways Cd36 participated on our site, such as PPAR signaling pathway, Phagosome, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PPAR signaling pathwayDBI;PDPK1B;ACOX1;ACSL4A;SCP2A;MMP1A;CYP27A1;UBC;ACSBG2
PhagosomeTUBA1C;ATP6V1C2;CLEC7A;VAMP3;HLA-DRB3;BF1;ITGB3;C3A.3;TUBA8L2
AMPK signaling pathwayPRKAA1;PPP2R5E;FASN;PRKAB1;CAB39;PRKAB2;EEF2;INSR;FBP2
ECM-receptor interactionSDC4;COL6A1;SDC1;COL4A4;Reln;COL27A1B;LAMA3;ITGA8;LAMB3
Hematopoietic cell lineageIL4R;CD22;CD33;FCGR1;GM-CSF;IL11RA;Il4ra;GM13305;IL7R
Adipocytokine signaling pathwayMAPK8B;STAT3;CAMKK2;PTPN11A;PRKCQ;RXRB;CPT1C;MAPK10;ACSL4
Insulin resistanceINSR;PIK3R3A;PRKCDA;SLC2A2;AKT2;PCK1;NR1H3;PIK3CD;PRKAG2A
Fat digestion and absorptionDGAT2;PLA2G12B;PPAP2A;PLA2G1B;PNLIPRP1;PPAP2B;PPAP2C;FABP2;PLA2G3
MalariaCD40LG;ITGB2L;GYPC;CD81;DARC;IFNG;CD40;HBB;MET

Cd36 has several biochemical functions, for example, MAP-kinase scaffold activity, kinesin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd36 itself. We selected most functions Cd36 had, and list some proteins which have the same functions with Cd36. You can find most of the proteins on our site.

Function Related Protein
MAP-kinase scaffold activityMAPK8IP3;DUSP19;SPAG9;JIP1;MAPK8IP2;SPAG9A;CD36;KSR1
kinesin bindingSERPINB1A;PLEKHM2;KCNC1;NUP62;ACTB;KIFAP3;NEFH;KIF1B;CLSTN1
protein bindingSPRTN;SSH1;RABIF;BCDIN3D;KIRREL3;ARHGDIA;HTN1;TRIM3;LANCL1
protein kinase bindingCRY1;CDC42;PTK2;CEP68;MEF2A;CCNL1;HDAC7A;PARN;CLTC
protein kinase inhibitor activityMBIP;TSACC;TRIB2;DUSP19;SH3BP5L;CHP1;SOCS6B;TESC;SOCS3B

Cd36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd36 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd36.

dacD; cutA; q7ciq1_yerpe; yapE; icc; CHRD; cona_canen

Puig, KL; Manocha, GD; et al. Amyloid Precursor Protein Mediated Changes in Intestinal Epithelial Phenotype In Vitro. PLOS ONE 10:-(2015).
He, L; Zhou, XM; et al. Comparative Study of the Growth and Survival of Recombinant Mycobacterium smegmatis Expressing Mce4A and Mce4E from Mycobacterium bovis. DNA AND CELL BIOLOGY 34:125-132(2015).
  • Q&As
  • Reviews

Q&As (7)

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What is the impact of CD36 on inflammation and the immune response, particularly in chronic inflammatory diseases? 01/23/2022

CD36 is involved in inflammation and immune responses, potentially exacerbating chronic inflammatory conditions.

How do alterations in CD36 expression or activity affect obesity and related health complications? 07/08/2021

Variations in CD36 function can influence the risk of obesity and associated health issues like metabolic syndrome.

What are the mechanisms by which CD36 modulates cell signaling and energy homeostasis? 03/15/2021

CD36 modulates cell signaling related to energy utilization and storage, impacting metabolic health.

How does CD36 contribute to the pathogenesis of metabolic disorders, such as insulin resistance and type 2 diabetes? 03/01/2021

CD36 affects the development of metabolic disorders by influencing lipid metabolism and insulin sensitivity.

How does CD36 influence taste perception, especially in the detection of dietary fats? 06/27/2020

CD36 aids in taste perception, particularly in detecting and responding to dietary fats.

What role does CD36 play in the development of cardiovascular diseases like atherosclerosis? 02/09/2020

CD36 is implicated in cardiovascular diseases, contributing to the formation of atherosclerotic plaques.

How does CD36 (Cluster of Differentiation 36) function in fatty acid metabolism and uptake? 08/27/2019

CD36 facilitates the uptake and metabolism of fatty acids in cells, playing a critical role in lipid processing.

Customer Reviews (3)

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Reviews
05/21/2020

    Dependable protein purification, consistently high-quality results.

    04/10/2019

      Great antibody validation, enhances our immunoprecipitation experiments.

      12/28/2018

        Swift protein expression optimization, invaluable for our research efficiency.

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