Recombinant Full Length Human CD8B Protein

Cat.No. : CD8B-65HF
Product Overview : Recombinant full length Human CD8 beta with a proprietary tag; Predicted MW 52.8 kDa inclusive of tag.
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Description : The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Source : In Vitro Cell Free System
Species : Human
Form : Liquid
Molecular Mass : 52.800kDa inclusive of tags
Protein Length : 243 amino acids
AA Sequence : MRPRLWLLLAAQLTVLHGNSVLQQT PAYIKVQTNKMVMLSCEAKISLSNM RIYWLRQRQAPSSDSHHEFLALWDS AKGTIHGEEVEQEKIAVFRDASRFI LNLTSVKPEDSGIYFCMIVGSPELT FGKGTQLSVVDFLPTTAQPTKKSTL KKRVCRLPRPETQKGPLCSPITLGL LVAGVLVLLVSLGVAIHLCCRRRRA RLRFMKQPQGEGISGTFVPQCLHGY YSNTTTSQKLLNPWILKT
Purity : Proprietary Purification
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer : pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.
Gene Name : CD8B CD8b molecule [ Homo sapiens ]
Official Symbol : CD8B
Synonyms : CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37) , CD8B1; T-cell surface glycoprotein CD8 beta chain
Gene ID : 926
mRNA Refseq : NM_001178100
Protein Refseq : NP_001171571
MIM : 186730
UniProt ID : P10966

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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