CX3CR1 Protein


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Official Full Name chemokine (C-X3-C motif) receptor 1
Background Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Synonyms CX3CR1; chemokine (C-X3-C motif) receptor 1; V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1; CX3C chemokine receptor 1; CMK-BRL1; CMK-BRL-1; C-X3-C CKR-1; fractalkine receptor; G protein-coupled receptor 13; G-protein coupled receptor 13; chemokine (C-X3-C) receptor 1; beta chemokine receptor-like 1; chemokine (C-C) receptor-like 1;
    • Species :
    • Bos taurus (Bovine)
    • Homo sapiens (Human)
    • Human
    • Mus musculus (Mouse)
    • Oryctolagus cuniculus (Rabbit)
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus Macaque
    • Source :
    • E. coli
    • E.coli expression system
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His/GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CX3CR1-2150H Recombinant Human CX3CR1 Protein, GST-tagged Wheat Germ GST Inquiry
    Human CX3CR1-28062TH Recombinant Human CX3CR1 Wheat Germ N/A Inquiry
    Rat CX3CR1-1684R Recombinant Rat CX3CR1 Protein Mammalian Cell His Inquiry
    Rhesus Macaque CX3CR1-1103R Recombinant Rhesus monkey CX3CR1 Protein, His-tagged Mammalian Cell His Inquiry
    Human CX3CR1-7173HCL Recombinant Human CX3CR1 293 Cell Lysate HEK293 N/A Inquiry
    Human CX3CR1-103HF Recombinant Full Length Human CX3CR1 Protein In Vitro Cell Free System Inquiry
    Human CX3CR1-2222HF Recombinant Full Length Human CX3CR1 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Rattus norvegicus (Rat) RFL16386RF Recombinant Full Length Rat Cx3C Chemokine Receptor 1(Cx3Cr1) Protein, His-Tagged E.coli expression system His Inquiry
    Homo sapiens (Human) RFL20493HF Recombinant Full Length Human Cx3C Chemokine Receptor 1(Cx3Cr1) Protein, His-Tagged E.coli expression system His Inquiry
    Mus musculus (Mouse) RFL26790MF Recombinant Full Length Mouse Cx3C Chemokine Receptor 1(Cx3Cr1) Protein, His-Tagged E.coli expression system His Inquiry
    Oryctolagus cuniculus (Rabbit) RFL26864OF Recombinant Full Length Rabbit Cx3C Chemokine Receptor 1(Cx3Cr1) Protein, His-Tagged E.coli expression system His Inquiry
    Bos taurus (Bovine) RFL26922BF Recombinant Full Length Bovine Cx3C Chemokine Receptor 1(Cx3Cr1) Protein, His-Tagged E.coli expression system His Inquiry
    Human CX3CR1-220H Recombinant Human CX3CR1 Protein, His/GST-tagged E. coli His/GST Inquiry
    Kit-1024 Tumor-derived Exosome enrichment and Quantification Assay Kit (Biological Fluids/Cell Media, Colorimetric) N/A Inquiry
    Kit-1187 CX3CR1 CHO-K1 β-Arrestin GPCR Assay Kit N/A Inquiry

    CX3CR1 involved in several pathways and played different roles in them. We selected most pathways CX3CR1 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CX3CR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine receptors bind chemokines CCBP2; CCR8; CCR3; CCL35.2; CXCL13; CCL35.1; CX3CR1; CCRL2; CXCL11.8; CCR6
    Chemokine signaling pathway PIK3R3; CXCL13; CXCL6; Cxcl15; CCR5; GRK7; AKT2; HRAS; CCR1; GNAI1
    Class A/1 (Rhodopsin-like receptors) NPB; RGR; KISS1; NMU; EDN2; CCRL2; CGA; OXER1; SSTR4; CXCR7B
    Cytokine-cytokine receptor interaction TNFSF13; TNFRSF18; IL3RA; IFNGR2; CCR5; CXCL12B; EPOR; IFNA7; IFNA1; VEGFB
    GPCRs, Class A Rhodopsin-like ADORA3; CNR2; GPR171; PTGDR2; GPR63; OPN1SW; OPN1MW2; SSTR5; CNR1; SSTR1
    Peptide GPCRs SSTR1; TAC4; SSTR4; SSTR5; CX3CR1; CXCR6
    Peptide ligand-binding receptors PRLH; SSTR1; APLNR; FPR-RS6; NPSR1; RLN3; TAC3; EDN3; GPR77; PENKA

    CX3CR1 has several biochemical functions, for example, C-X3-C chemokine receptor activity, chemokine receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CX3CR1 itself. We selected most functions CX3CR1 had, and list some proteins which have the same functions with CX3CR1. You can find most of the proteins on our site.

    Function Related Protein
    C-X3-C chemokine receptor activity CX3CR1
    chemokine receptor activity ACKR3B; CX3CR1; ACKR4; CXCR4A; CCBP2; GPR17; CXCR3.2; CCR9; CCR6; CCR3
    protein binding TMEM106B; TXNRD3; CSRP3; CDK13; UBLCP1; NOG; PCSK5; APOBEC3C; CLPTM1; SLC7A1

    CX3CR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CX3CR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CX3CR1.

    Sugaya, M; et al. Chemokines and Skin Diseases. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS 63:109-115(2015).
    Bian, C; Zhao, ZQ; et al. Involvement of CX3CL1/CX3CR1 Signaling in Spinal Long Term Potentiation. PLOS ONE 10:-(2015).

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