Recombinant Full Length Human CX3CR1 Protein
Cat.No. : | CX3CR1-103HF |
Product Overview : | Recombinant full length Human CX3CR1 protein with a proprietary tag; predicted mwt: 65.12 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 65.120kDa |
Protein Length : | 355 amino acids |
AA Sequence : | MDQFPESVTENFEYDDLAEACYIGD IVVFGTVFLSIFYSVIFAIGLVGNL LVVFALTNSKKPKSVTDIYLLNLAL SDLLFVATLPFWTHYLINEKGLHNA MCKFTTAFFFIGFFGSIFFITVISI DRYLAIVLAANSMNNRTVQHGVTIS LGVWAAAILVAAPQFMFTKQKENEC LGDYPEVLQEIWPVLRNVETNFLGF LLPLLIMSYCYFRIIQTLFSCKNHK KAKAIKLILLVVIVFFLFWTPYNVM IFLETLKLYDFFPSCDMRKDLRLAL SVTETVAFSHCCLNPLIYAFAGEKF RRYLYHLYGKCLAVLCGRSVHVDFS SSESQRSRHGSVLSSNFTYHTSDGD ALLLL |
Purity : | Proprietary Purification |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
Storage Buffer : | Constituents: 0.79% Tris HCl, 0.31% Glutathione. Note: Reduced Glutathione. |
Gene Name : | CX3CR1 chemokine (C-X3-C motif) receptor 1 [ Homo sapiens ] |
Official Symbol : | CX3CR1 |
Synonyms : | CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28 |
Gene ID : | 1524 |
mRNA Refseq : | NM_001171171 |
Protein Refseq : | NP_001164642 |
MIM : | 601470 |
UniProt ID : | P49238 |
Products Types
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CX3CR1-2150H | Recombinant Human CX3CR1 Protein, GST-tagged | +Inquiry |
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◆ Lysates | ||
CX3CR1-7173HCL | Recombinant Human CX3CR1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1187 | CX3CR1 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionThere are potential therapeutic implications related to CX3CR1 in immune-related disorders, making it a target of interest for drug development.
CX3CR1 contributes to the regulation of immune responses and cell migration by responding to its ligand, fractalkine (CX3CL1).
CX3CR1 is predominantly expressed in certain immune cells, including monocytes, macrophages, and certain subsets of T cells.
CX3CR1 plays a role in influencing the balance between immune tolerance and inflammation through its impact on immune cell function.
Dysregulation or abnormal expression of CX3CR1 is associated with conditions such as atherosclerosis, neuroinflammatory disorders, and certain cancers.
The ligand for CX3CR1, fractalkine (CX3CL1), is involved in immune modulation, influencing cell adhesion and migration.
C-X3-C motif chemokine receptor 1 (CX3CR1) primarily functions in the immune system, playing a role in immune responses and cell migration.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.
The reliability of the product's quality and effectiveness from one batch to another instilled confidence in its usage.
The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.
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