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Recombinant Full Length Human CX3CR1 Protein

Cat.No. : CX3CR1-103HF
Product Overview : Recombinant full length Human CX3CR1 protein with a proprietary tag; predicted mwt: 65.12 kDa.
  • Specification
  • Gene Information
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Description : Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Source : In Vitro Cell Free System
Species : Human
Form : Liquid
Molecular Mass : 65.120kDa
Protein Length : 355 amino acids
AA Sequence : MDQFPESVTENFEYDDLAEACYIGD IVVFGTVFLSIFYSVIFAIGLVGNL LVVFALTNSKKPKSVTDIYLLNLAL SDLLFVATLPFWTHYLINEKGLHNA MCKFTTAFFFIGFFGSIFFITVISI DRYLAIVLAANSMNNRTVQHGVTIS LGVWAAAILVAAPQFMFTKQKENEC LGDYPEVLQEIWPVLRNVETNFLGF LLPLLIMSYCYFRIIQTLFSCKNHK KAKAIKLILLVVIVFFLFWTPYNVM IFLETLKLYDFFPSCDMRKDLRLAL SVTETVAFSHCCLNPLIYAFAGEKF RRYLYHLYGKCLAVLCGRSVHVDFS SSESQRSRHGSVLSSNFTYHTSDGD ALLLL
Purity : Proprietary Purification
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer : Constituents: 0.79% Tris HCl, 0.31% Glutathione. Note: Reduced Glutathione.
Gene Name : CX3CR1 chemokine (C-X3-C motif) receptor 1 [ Homo sapiens ]
Official Symbol : CX3CR1
Synonyms : CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28
Gene ID : 1524
mRNA Refseq : NM_001171171
Protein Refseq : NP_001164642
MIM : 601470
UniProt ID : P49238

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there therapeutic implications or potential targets related to CX3CR1 in immune-related disorders? 07/27/2022

There are potential therapeutic implications related to CX3CR1 in immune-related disorders, making it a target of interest for drug development.

How does CX3CR1 contribute to the regulation of immune responses and cell migration? 02/23/2019

CX3CR1 contributes to the regulation of immune responses and cell migration by responding to its ligand, fractalkine (CX3CL1).

In which immune cells is CX3CR1 predominantly expressed? 10/21/2018

CX3CR1 is predominantly expressed in certain immune cells, including monocytes, macrophages, and certain subsets of T cells.

How does CX3CR1 influence the balance between immune tolerance and inflammation? 04/04/2018

CX3CR1 plays a role in influencing the balance between immune tolerance and inflammation through its impact on immune cell function.

What diseases or conditions are associated with dysregulation or abnormal expression of CX3CR1? 11/16/2017

Dysregulation or abnormal expression of CX3CR1 is associated with conditions such as atherosclerosis, neuroinflammatory disorders, and certain cancers.

Are there specific chemokines that bind to CX3CR1, and what is their role in immune modulation? 12/04/2016

The ligand for CX3CR1, fractalkine (CX3CL1), is involved in immune modulation, influencing cell adhesion and migration.

What is the primary function of C-X3-C motif chemokine receptor 1 (CX3CR1) in the immune system? 10/19/2016

C-X3-C motif chemokine receptor 1 (CX3CR1) primarily functions in the immune system, playing a role in immune responses and cell migration.

Customer Reviews (3)

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Reviews
09/06/2016

    The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.

    04/21/2016

      The reliability of the product's quality and effectiveness from one batch to another instilled confidence in its usage.

      02/08/2016

        The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.

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