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Recombinant Human CX3CR1 Protein, His/GST-tagged

Cat.No. : CX3CR1-220H
Product Overview : Recombinant Human CX3CR1 Protein(NP_001164642.1)(Met1~Lys103), fused with N-terminal His and GST tag, was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His/GST
Form : 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Molecular Mass : 42kDa as determined by SDS-PAGE reducing conditions.
Protein length : Met1~Lys103
AA Sequence : MDQFPESVTENFEYDDLAEACYIGD IVVFGTVFLSIFYSVIFAIGLVGNL LVVFALTNSKKPKSVTDIYLLNLAL SDLLFVATLPFWTHYLINEKGLHNA MCK
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200µg/mL
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : CX3CR1 C-X3-C motif chemokine receptor 1 [ Homo sapiens (human) ]
Official Symbol : CX3CR1
Synonyms : V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1
Gene ID : 1524
mRNA Refseq : NM_001171171.2
Protein Refseq : NP_001164642.1
MIM : 601470
UniProt ID : P49238

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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