FGF13

  • Official Full Name

    fibroblast growth factor 13

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5 end results in several transcript variants encoding different isoforms with different N-termini.
  • Synonyms

    FGF13; fibroblast growth factor 13; FGF2; FHF2; fibroblast growth factor homologous factor 2; FGF 13; FGF 2; FGF-13; FGF13_HUMAN; FHF 2; FHF-2; OTTHUMP00000024143; OTTHUMP00000024144;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF13-27598TH Recombinant Human FGF13 Wheat Germ N/A 245 amino acids
Human FGF13-8155H Recombinant Human FGF13 protein, His-tagged E.coli His Glu63~Thr245 (Accession # Q92913)
Human FGF13-12863H Recombinant Human FGF13, GST-tagged E.coli GST 1-245a.a.
Human FGF13-521H Recombinant Human FGF13 protein E.coli N/A 245
Human FGF13-6248HCL Recombinant Human FGF13 293 Cell Lysate HEK293 N/A
Human FGF13-168HF Recombinant Full Length Human FGF13 Protein In Vitro Cell Free System 245 amino acids
Human FGF13-4103H Recombinant Human FGF13 Protein, GST-tagged Wheat Germ GST
Human FGF13-2187H Recombinant Human FGF13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGF13-12865H Recombinant Human FGF13 protein(212-245 aa), His-tagged E. coli N-His 212-245 aa
Human FGF13-12864H Recombinant Human FGF13 protein(212-245 aa), GST-tagged E. coli N-GST 212-245 aa
Human FGF13-027H Recombinant Human FGF13 Protein E.coli
Human FGF13-2907H Recombinant Human FGF13 protein, His-tagged E.coli His 1-245aa
Human FGF13-4810HF Recombinant Full Length Human FGF13 Protein, GST-tagged In Vitro Cell Free System GST 245 amino acids
Human FGF13-2768H Recombinant Human FGF13 Protein (Gly108-Arg227), N-His tagged E.coli N-His Gly108-Arg227
Human FGF13-106H Active Recombinant Human FGF13 Protein (Met1-Thr245), C-His tagged, Animal-free, Carrier-free E.coli C-His Met1-Thr245
Mouse FGF13-5841M Recombinant Mouse FGF13 Protein Mammalian Cell His
Mouse Fgf13-2994M Recombinant Mouse Fgf13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FGF13-3228M Recombinant Mouse FGF13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FGF13-3228M-B Recombinant Mouse FGF13 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF13-2326R Recombinant Rat FGF13 Protein Mammalian Cell His
Rat Fgf13-8156R Recombinant Rat Fgf13 protein, His-tagged E.coli His Met1~Thr192 (Accession # Q9ERW3)
Rat FGF13-1983R-B Recombinant Rat FGF13 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF13-1983R Recombinant Rat FGF13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGF13-1695R Recombinant Rhesus monkey FGF13 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGF13-1517R Recombinant Rhesus Macaque FGF13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGF13-1517R-B Recombinant Rhesus Macaque FGF13 Protein Pre-coupled Magnetic Beads HEK293
Chicken FGF13-1139C Recombinant Chicken FGF13 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FGF13 Related Signal Pathway

FGF13 involved in several pathways and played different roles in them. We selected most pathways FGF13 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayMAPK14A;FGF2;TAB2;HSPA1B;MAPK12A;PAK2B;CACNA1BA;RPS6KA2;TGFB3
Ras signaling pathwayRASSF5;CALM4;EFNA4;IKBKG;FIGF;GNG10;PRKACG;FGF5;VEGFB
Rap signaling pathwayFGF14;PGF;SIPA1L2;SIPA1L1;ITGB2L;MAGI2;PRKCI;PIK3R3;LPAR4
PIK-Akt signaling pathwayVEGFC;RPS6KB1;TSC1;GYS2;RAF1;NOS3;IFNA17;LAMB3;FGF3
Regulation of actin cytoskeletonPPP1R12A;PDGFB;FGD;FGF3;MYL9A;PDGFRB;GNG12A;DIAPH3;ITGA7
Pathways in cancerAPC;EGLN2;NKX3-1;PLEKHG5;ITGB1;BCL2;LAMB2;FH;HHIP
MelanomaCCND1;BRAF;KRAS;PIK3R1;FGF2;FGF17;MET;PDGFRB;FGF6

FGF13 has several biochemical functions, for example, beta-tubulin binding, growth factor activity, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF13 itself. We selected most functions FGF13 had, and list some proteins which have the same functions with FGF13. You can find most of the proteins on our site.

Function Related Protein
beta-tubulin bindingCASC1;SLC6A2;GABARAPL1;VAPB;GABARAPL2;OST4;PROL1;ADNP;BBS4
growth factor activityPDGFB;REG1A;INHBE;OGN;FGF20;GFER;FGF20B;FGF1A;JAG2
ion channel bindingKCNAB1;ANK2;RIMS1;PIRT;PKD1;TCAP;EPN1;KCNE4;FXYD1
microtubule bindingMAP1LC3C;GABARAPL1;MARK4;MAPRE3B;SPAG8;MAP6;KIF9;RGS14;HDAC6
protein bindingTK1;AP1S2;NMRK1;MRPS27;THOC4;AP5S1;PAGE2;CNTF;IRF2BP1
protein kinase activator activityDBF4B;MT3;STK11;AGAP2;EPO;DAXX;NKX3;STRADA;DUSP19
sodium channel regulator activityFXYD5;SGK3;FXYD4;GPD1L;FGF13;FXYD1;FXYD3;RANGRF;FXYD6

FGF13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF13 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF13.

PRNP; CLEC3B; MAPK8IP2

Research Area

Related articles

Davidov, T; Nagar, M; et al. Carbonic anhydrase 4 and crystallin alpha-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology. JOURNAL OF SURGICAL RESEARCH 190:565-574(2014).
Tyler, CR; Allan, AM; et al. Prenatal alcohol exposure alters expression of neurogenesis-related genes in an ex vivo cell culture model. ALCOHOL 48:483-492(2014).
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