fgf13

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fgf13

Official Full Name fibroblast growth factor 13
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5 end results in several transcript variants encoding different isoforms with different N-termini.
Synonyms FGF13; fibroblast growth factor 13; FGF2; FHF2; fibroblast growth factor homologous factor 2; FGF 13; FGF 2; FGF-13; FGF13_HUMAN; FHF 2; FHF-2; OTTHUMP00000024143; OTTHUMP00000024144
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF13-12863H Recombinant Human FGF13, GST-tagged E.coli GST
    Human FGF13-2187H Recombinant Human FGF13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human FGF13-27598TH Recombinant Human FGF13 Wheat Germ N/A
    Human FGF13-4103H Recombinant Human FGF13 Protein, GST-tagged Wheat Germ GST
    Human FGF13-521H Recombinant Human FGF13 protein E.coli N/A
    Human FGF13-6248HCL Recombinant Human FGF13 293 Cell Lysate HEK293 N/A
    Human FGF13-8155H Recombinant Human FGF13 protein, His-tagged E.coli His
    Mouse Fgf13-2994M Recombinant Mouse Fgf13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse FGF13-5841M Recombinant Mouse FGF13 Protein Mammalian Cell His
    Rat FGF13-2326R Recombinant Rat FGF13 Protein Mammalian Cell His
    Rat Fgf13-8156R Recombinant Rat Fgf13 protein, His-tagged E.coli His
    Rhesus Macaque FGF13-1695R Recombinant Rhesus monkey FGF13 Protein, His-tagged Mammalian Cell His
    Chicken FGF13-1139C Recombinant Chicken FGF13 Mammalian Cell His

    fgf13 involved in several pathways and played different roles in them. We selected most pathways fgf13 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fgf13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway TGFB1A; FGFR4; NLK; PAK2A; MAPK8B; MAP2K2A; PPP3CC; KCNA3; IL1R1; TNF
    Ras signaling pathway PIK3R1; FGF19; ETS2; BRAP; FLT4; MRAS; CALM4; FGF2; RAC3; INS2
    Rap signaling pathway MAP2K1; RAPGEF5; RAPGEF1; SIPA1L2; PRKCA; FGF3; LPAR2; GNAS; PDGFD; KRIT1
    PIK-Akt signaling pathway LPAR3; GNB1; PPP2R1A; IFNA17; IL7R; MAPK1; G6PC3; FGFR4; LAMB3; FGF6
    Regulation of actin cytoskeleton ARHGAP35; ITGB1B.2; ITGAL; ABI2B; ITGB3B; FGFR4; WASB; ARPC5A; RAC1; PAK7
    Pathways in cancer ARAF; FH; FGFR3; FGF3; AKT2; HRAS; FZD2; AGTR1A; KIT; PIK3R2
    Melanoma FGF12; FGF8; PIK3R2; PIK3CG; MITF; FGF3; PDGFB; FGF9; ARAF; MET

    fgf13 has several biochemical functions, for example, beta-tubulin binding, growth factor activity, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fgf13 itself. We selected most functions fgf13 had, and list some proteins which have the same functions with fgf13. You can find most of the proteins on our site.

    Function Related Protein
    beta-tubulin binding ARL8A; PACRG; BBS4; GABARAP; PROL1; RANBP10; PDCD5; ARL8B; CCT5; CASC1
    growth factor activity GRN; TIMP1; GPR19; TGFA; IL6; MDK; KLK1B3; AREG; FGF11; NRG1
    ion channel binding AASS; KCNB2; ACTN2; CALM3; CHERP; PACS1A; KCNH5; CALM; FXYD1; PDE4B
    microtubule binding FMN1; DNM2; KCNH2A; TUBGCP5; GOLGA2; KIF26A; MID1; HAUS8; CAMSAP1A; MTAP1B
    protein binding TARSL2; TMPRSS7; SMAD9; COIL; SPG7; PDLIM4; LARP7; UBE2N; ADAMTS13; LDHD
    protein kinase activator activity FGF13; FAM58A; AGAP2; PIK3CA; CAB39; DBF4B; NKX3-1; STRADA; WNT11; TOM1L1
    sodium channel regulator activity SCN1B; SCN1BA; SGK2; FXYD4; FXYD1; SCN3B; FXYD2; SGK1; FXYD7; FGF12

    fgf13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fgf13 here. Most of them are supplied by our site. Hope this information will be useful for your research of fgf13.

    PRNP; CLEC3B; MAPK8IP2

    Davidov, T; Nagar, M; et al. Carbonic anhydrase 4 and crystallin alpha-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology. JOURNAL OF SURGICAL RESEARCH 190:565-574(2014).
    Tyler, CR; Allan, AM; et al. Prenatal alcohol exposure alters expression of neurogenesis-related genes in an ex vivo cell culture model. ALCOHOL 48:483-492(2014).

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