FGF13 involved in several pathways and played different roles in them. We selected most pathways FGF13 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| MAPK signaling pathway |
MAP4K2; MAPK7; MAX; MKNK1; FGF8; ELK4; RAP1A; CACNA1DA; MAP3K11; NTRK1 |
| Ras signaling pathway |
KLK1B4; GNB3; Kitl; CALM4; RAC1; VEGFA; PIK3CA; GNG11; PLD1; KSR2 |
| Rap signaling pathway |
BRAF; BCAR1; MAGI2; APBB1IP; CALML5; HRAS; CALM1; GRIN2B; Adcy4; PRKCI |
| PIK-Akt signaling pathway |
FASLG; TCL1B4; TLR4; GHR; FGF5; GNG10; PHLPP1; LAMA5; IFNA16; ITGA1 |
| Regulation of actin cytoskeleton |
MYL9A; BCAR1; PIK3R3B; FGF22; PIP5K2; ITGA7; MSNB; ITGB5; PDGFD; FGF6 |
| Pathways in cancer |
FGF12; GSK3B; HSP90B1; PLCB1; FGF14; CCDC6; STK36; PTK2; GNB1; WNT1 |
| Melanoma |
FGF16; FGF6; AKT1; FGF10; FGF20; FGF14; TP53; MDM2; PTEN; PDGFRA |
FGF13 has several biochemical functions, for example, beta-tubulin binding, growth factor activity, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF13 itself. We selected most functions FGF13 had, and list some proteins which have the same functions with FGF13. You can find most of the proteins on our site.
| Function |
Related Protein |
| beta-tubulin binding |
IFT74; RACGAP1; RANBP10; NDEL1; SNCA; FGF13; GABARAPL1; HDAC6; CCT5; SERPINB1A |
| growth factor activity |
BMP2; GDF6B; NRG4; NOV; FGF12; GFER; IGF3; MDKB; FGF11A; OSM |
| ion channel binding |
PRNP; KCNB1; LYN; PACS2; CAV3; AP2M1; AKAP6; DIAP1; SRI; CTNNB1 |
| microtubule binding |
NDEL1A; CHP1; ARHGEF2; CKAP5; TRAF3IP1; MAP6; JAKMIP3; CLASP1; JAKMIP2; CNN3 |
| protein binding |
CRHR2; EFHC2; CIAPIN1; KCP; STOML1; CHRM3; DDI1; CACFD1; MAP4K5; XK |
| protein kinase activator activity |
EPO; DUSP19; STRADA; PRKAG2; CAB39; DBF4B; AGAP2; STK11; MAPK8IP2; DAXX |
| sodium channel regulator activity |
FXYD2; FXYD6; SCN3B; CAV3; FGF12; FXYD4; PRSS30; YWHAH; SCLT1; GPLD1 |
FGF13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF13 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF13.
PRNP; CLEC3B; MAPK8IP2
Davidov, T; Nagar, M; et al. Carbonic anhydrase 4 and crystallin alpha-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology. JOURNAL OF SURGICAL RESEARCH 190:565-574(2014).
Tyler, CR; Allan, AM; et al. Prenatal alcohol exposure alters expression of neurogenesis-related genes in an ex vivo cell culture model. ALCOHOL 48:483-492(2014).
