FZD7 Protein


Home / Products / FZD7


Official Full Name frizzled class receptor 7
Background Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
Synonyms FZD7; frizzled class receptor 7; FzE3; frizzled-7; fz-7; hFz7; frizzled homolog 7; frizzled family receptor 7; Frizzled, drosophila, homolog of, 7; frizzled 7, seven transmembrane spanning receptor;
    • Species :
    • Chicken
    • Gallus gallus (Chicken)
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
    • Source :
    • CHO
    • E.coli expression system
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • His&Flag
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FZD7-537H Active Recombinant Human FZD7 Protein, Fc-tagged CHO Fc Inquiry
    Mouse Fzd7-589M Active Recombinant Mouse Frizzled Homolog 7 (Drosophila), Fc-tagged Mammalian cells Fc Inquiry
    Human FZD7-12H Recombinant Human FZD7 protein, Fc-tagged HEK293 human/IgG1/Fc Inquiry
    Human FZD7-26288TH Recombinant Human FZD7 Wheat Germ N/A Inquiry
    Human FZD7-643H Recombinant Human FZD7 protein, His-tagged HEK293 His Inquiry
    Mouse FZD7-6121M Recombinant Mouse FZD7 Protein Mammalian Cell His Inquiry
    Chicken FZD7-5794C Recombinant Chicken FZD7 Mammalian Cell His Inquiry
    Human FZD7-6088HCL Recombinant Human FZD7 293 Cell Lysate HEK293 N/A Inquiry
    Human FZD7-1113HFL Recombinant Human FZD7 protein, His&Flag-tagged HEK293 His&Flag Inquiry
    Human FZD7-5090HF Recombinant Full Length Human FZD7 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Human FZD7-6193HF Recombinant Full Length Human FZD7 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Gallus gallus (Chicken) RFL19638GF Recombinant Full Length Chicken Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Inquiry
    Mus musculus (Mouse) RFL20929MF Recombinant Full Length Mouse Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Inquiry
    Homo sapiens (Human) RFL2311HF Recombinant Full Length Human Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Inquiry
    Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL33853XF Recombinant Full Length Xenopus Tropicalis Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Inquiry
    Human FZD7-4598H Recombinant Human FZD7 Protein, GST-tagged Wheat Germ GST Inquiry
    Human FZD7-2166H Recombinant Human FZD7 Protein, GST-tagged Wheat Germ GST Inquiry

    FZD7 involved in several pathways and played different roles in them. We selected most pathways FZD7 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway PLCB1; CCND2; SFRP1A; PRKCB; FBXW11A; TLE3A; WNT4A; BAMBI; TBL1XR1; SFRP5
    Hippo signaling pathway LATS2; YWHAZ; WNT5B; TGFB1; PPP2R2C; AJUBA; FZD3; WNT3A; TGFB3; TEAD4
    Signaling pathways regulating pluripotency of stem cells HESX1; KLF4; WNT16; FGFR3; FZD5; ACVR2B; Fzd4; WNT1; AXIN2; WNT4
    Melanogenesis RAF1B; TYRP1; GNAI2; FZD8B; LEF1; CREB3L2; CREB3L1; GNAI2B; EP300; GNA15.4
    Pathways in cancer CKS2; Flt3l; FIGF; GSK3B; PRKACG; MMP2; ARHGEF12; PTCH2; SUFU; ITGB1
    Proteoglycans in cancer VAV2; PPP1CA; FLNC; CBL; Ctsl; WNT16; FZD5; PIK3CA; SMAD2; TWIST2
    Basal cell carcinoma WNT3A; SUFU; LEF1; AXIN1; WNT5B; WNT7A; WNT8A; FZD1; APC; FZD6

    FZD7 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD7 itself. We selected most functions FZD7 had, and list some proteins which have the same functions with FZD7. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity ADRB3A; GPR34A; GPR81; TAAR9; PTGDR2; GPR62; GHSR; OR8A1; PPYR1; V2RH14
    PDZ domain binding CCDC88C; DLG4; ADAM17; KIDINS220; PSEN1; ERC1; CXXC4; GJA1; FZD2; SRR
    Wnt-activated receptor activity FZD10; FZD8; LRP5; FZD5; FZD7B; FZD7; FZD1; LRP6; FZD9; LRP2A
    Wnt-protein binding FZD6; GPR177; FZD8; LRP5L; FZD7; LRP5; ROR2; FZD9; LRP6; FZD2
    frizzled binding WNT7AA; WNT2B; RSPO3; DVL2; WNT10B; DVL1B; DVL3; SDCBP; FZD1; SFRP1
    protein binding CALCR; HSPE1; NONO; GTF3C3; CATSPERG2; AKAP12; ZNF502; IL5RA; FZR1; CYB5R1

    FZD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD7.

    SDCBP; WNT3; sdcbp; C1qa; UBQLN4; UBQLN1

    Yuan, K; Orcholski, ME; et al. Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis. AMERICAN JOURNAL OF PATHOLOGY 185:69-84(2015).
    Ross, J; Busch, J; et al. A Rare Human Syndrome Provides Genetic Evidence that WNT Signaling Is Required for Reprogramming of Fibroblasts to Induced Pluripotent Stem Cells. CELL REPORTS 9:1770-1780(2014).

    Q&As (0)

    Ask a Question for All FZD7 Products

    Required fields are marked with *

    • Verification Code

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy