Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

FZD7

  • Official Full Name

    frizzled class receptor 7

  • Overview

    Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
  • Synonyms

    FZD7; frizzled class receptor 7; FzE3; frizzled-7; fz-7; hFz7; frizzled homolog 7; frizzled family receptor 7; Frizzled, drosophila, homolog of, 7; frizzled 7, seven transmembrane spanning receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Gallus gallus (Chicken)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • CHO
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Fc
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • Flag
  • human|IgG1|Fc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FZD7-537H Active Recombinant Human FZD7 Protein, Fc-tagged CHO Fc Gln33 - Leu185
Human FZD7-384H Active Recombinant Human FZD7 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human FZD7-26288TH Recombinant Human FZD7 Wheat Germ N/A 99 amino acids
Human FZD7-643H Active Recombinant Human FZD7 protein, His-tagged HEK293 His Gln33-Leu185
Human FZD7-12H Recombinant Human FZD7 protein, Fc-tagged HEK293 human/IgG1/Fc Gln33-Leu185
Human FZD7-6088HCL Recombinant Human FZD7 293 Cell Lysate HEK293 N/A
Human FZD7-5090HF Recombinant Full Length Human FZD7 Protein, GST-tagged In Vitro Cell Free System GST 574 amino acids
Human FZD7-4598H Recombinant Human FZD7 Protein, GST-tagged Wheat Germ GST
Human FZD7-1113HFL Recombinant Human FZD7 protein, His&Flag-tagged HEK293 His&Flag 1-574 aa
Human FZD7-2166H Recombinant Human FZD7 Protein, GST-tagged Wheat Germ GST
Human FZD7-6193HF Recombinant Full Length Human FZD7 Protein, GST-tagged In Vitro Cell Free System GST 574 amino acids
Human FZD7-2704H Active Recombinant Human FZD7 protein, hFc&His-tagged HEK293 hFc&His Gln33-Leu185
Human FZD7-1470H Recombinant Human FZD7 protein, Fc-tagged HEK293 Fc Gln33-Leu185
Human FZD7-258H Recombinant Human FZD7 Protein, Fc-tagged HEK293 Fc 574
Mouse Fzd7-589M Active Recombinant Mouse Frizzled Homolog 7 (Drosophila), Fc-tagged Mammalian cells Fc
Mouse FZD7-6121M Recombinant Mouse FZD7 Protein Mammalian Cell His
Mouse Fzd7-54M Recombinant Mouse Fzd7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fzd7-54M-B Recombinant Mouse Fzd7 Protein Pre-coupled Magnetic Beads HEK293
Gallus gallus (Chicken) RFL19638GF Recombinant Full Length Chicken Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (32-567)
Homo sapiens (Human) RFL2311HF Recombinant Full Length Human Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-574)
Mus musculus (Mouse) RFL20929MF Recombinant Full Length Mouse Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-572)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL33853XF Recombinant Full Length Xenopus Tropicalis Frizzled-7(Fzd7) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-548)
Chicken FZD7-5794C Recombinant Chicken FZD7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FZD7 Related Articles
  • FZD7 Related Gene Family
  • FZD7 Related Signal Pathway

FZD7 involved in several pathways and played different roles in them. We selected most pathways FZD7 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayFZD7B;SENP2;PPP3R2;AXIN1;RHOAB;FZD8B;WNT2BA;MAPK8B;SMAD4
Hippo signaling pathwayBMP5;AMH;YWHAG;PPP2R2D;YWHAH;TCF7L2;TCF7;LEF1;APC2
Signaling pathways regulating pluripotency of stem cellsPOU5F1;MYF5;IGF1R;AKT2;PIK3CD;WNT3A;WNT11;WNT3;PAX6
MelanogenesisFZD2;WNT2BB;FZD10;GNAIA;CALM1B;PRKCA;CALM3B;MAP2K2A;PLCB4
HTLV-I infectionXPO1;BCL2L1;HLA-DMA;IKBKG;ITGAL;POLE4;GPS2;HLA-DQA1;CCNB2
Pathways in cancerRB1;MAP2K2;RASGRP3;MSH2;ITGA2B;ARHGEF12;AXIN2;CCNA1;FZD2
Proteoglycans in cancerWNT4;TWIST1;ERBB3;PLAUR;CAMK2A;TNF;RRAS2;CCND1;PLCE1
Basal cell carcinomaTCF7;WNT2B;BMP4;FZD5;GSK3B;GLI3;FZD10;WNT16;APC2

FZD7 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD7 itself. We selected most functions FZD7 had, and list some proteins which have the same functions with FZD7. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityLPAR2;OLFR482;TAAR4;GPR146;GPR171;GPR18;MRGPRB8;OLFR8;GPR37B
PDZ domain bindingNSF;LRP2;BAIAP2;KIDINS220;LPAR1;NLGN1;TBC1D10A;PTENA;CFTR
Wnt-activated receptor activityFZD8;FZD7;FZD3B;FZD7B;LRP5L;FZD3;FZD10;LRP6;LRP2A
Wnt-protein bindingAPCDD1;FZD9B;FZD9;FZD5;EVLA;ROR2;LRP6;SZL;ROR1
frizzled bindingWNT1;ZNRF3;WNT2BB;WNT2B;RSPO3;DVL3A;NDP;WNT2BA;FZD7
protein bindingDALRD3;UCP2;HDGF2;SPATA24;CABLES1;POLE3;PARP2;TRDN;ZC3HAV1

FZD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD7.

SDCBP; WNT3; sdcbp; C1qa; UBQLN4; UBQLN1

Yuan, K; Orcholski, ME; et al. Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis. AMERICAN JOURNAL OF PATHOLOGY 185:69-84(2015).
Ross, J; Busch, J; et al. A Rare Human Syndrome Provides Genetic Evidence that WNT Signaling Is Required for Reprogramming of Fibroblasts to Induced Pluripotent Stem Cells. CELL REPORTS 9:1770-1780(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All FZD7 Products

Required fields are marked with *

My Review for All FZD7 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends