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Recombinant Full Length Human FZD7 Protein, GST-tagged

Cat.No. : FZD7-5090HF
Product Overview : Human FZD7 full-length ORF ( AAH15915.1, 1 a.a. - 574 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 88.77 kDa
Protein Length : 574 amino acids
AA Sequence : MRDPGAAAPLSSLGLCALVLALLGA LSAGAGAQPYHGEKGISVPDHGFCQ PISIPLCTDIAYNQTILPNLLGHTN QEDAGLEVHQFYPLVKVQCSPELRF FLCSMYAPVCTVLDQAIPPCRSLCE RARQGCEALMNKFGFQWPERLRCEN FPVHGAGEICVGQNTSDGSGGPGGG PTAYPTAPYLPDLPFTALPPGASDG RGRPAFPFSCPRQLKVPPYLGYRFL GERDCGAPCEPGRANGLMYFKEEER RFARLWVGVWSVLCCASTLFTVLTY LVDMRRFSYPERPIIFLSGCYFMVA VAHVAGFLLEDRAVCVERFSDDGYR TVAQGTKKEGCTILFMVLYFFGMAS SIWWVILSLTWFLAAGMKWGHEAIE ANSQYFHLAAWAVPAVKTITILAMG QVDGDLLSGVCYVGLSSVDALRGFV LAPLFVYLFIGTSFLLAGFVSLFRI RTIMKHDGTKTEKLEKLMVRIGVFS VLYTVPATIVLACYFYEQAFREHWE RTWLLQTCKSYAVPCPPGHFPPMSP DFTVFMIKYLMTMIVGITTGFWIWS GKTLQSWRRFYHRLSHSSKGETAV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FZD7 frizzled family receptor 7 [ Homo sapiens ]
Official Symbol : FZD7
Synonyms : FZD7; frizzled family receptor 7; frizzled (Drosophila) homolog 7, frizzled 7, seven transmembrane spanning receptor, frizzled homolog 7 (Drosophila); frizzled-7; FzE3; fz-7; hFz7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; frizzled 7, seven transmembrane spanning receptor;
Gene ID : 8324
mRNA Refseq : NM_003507
Protein Refseq : NP_003498
MIM : 603410
UniProt ID : O75084

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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