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  • Official Full Name
  • genderblind
  • Background
  • Human cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B is a 907-amino acid glycoprotein encoded by the ORF of UL55. It is the most abundant component of the envelope with at least two defined neutralizing epitopes, a target of neutralizing antibodies and an essential replication component. The synthesized gB precursor matures into a 130-160 kDa glycoprotein by acquiring N-linked glycosylation modifications, and is cleaved by the cellular protease furin into two components, a 93-116 kDa N-terminal fragment and a 55 kDa C-terminal fragment linked by a disulfide-bond, which is presented on the viral envelope as well as on the surface of virus-infected cells as a covalently associated homodimer. gB plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. It triggers penetration of cells and enhances the spread of infection in nonpolarized human fibroblasts.
  • Synonyms
  • Glycoprotein B
Cat.#:gB-1698VTag:
Source (Host):HEK293Species:VZV
Product nameRecombinant VZV gB Protein
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Cat.#:gB-112CTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human cytomegalovirus gB
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Cat.#:gB-109CTag:Fc
Source (Host):HEK293Species:CMV
Product nameRecombinant CMV gB, Fc tagged
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Cat.#:gB-110CTag:His
Source (Host):HEK293Species:CMV
Product nameRecombinant CMV gB, His tagged
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Cat.#:gB-111CTag:His/GST
Source (Host):HEK293Species:CMV
Product nameRecombinant CMV gB, His & GST tagged
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Cat.#:GB-18HTag:Fc
Source (Host):HEK293Species:Human cytomegalovirus
Product nameRecombinant Human cytomegalovirus GB protein, Fc-tagged
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Cat.#:gB-352VTag:GST
Source (Host):E. coliSpecies:CMV
Product nameRecombinant CMV gB Protein, GST-tagged
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Cat.#:gB-457VTag:
Source (Host):E. coliSpecies:HSV-2
Product nameRecombinant HSV-2 gB Protein
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Cat.#:gB-501VTag:
Source (Host):E.coliSpecies:HSV-1
Product nameRecombinant HSV-1 gB Protein
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Cat.#:gB-520VTag:
Source (Host):E.coliSpecies:PRV
Product nameRecombinant PRV gB Protein
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Cat.#:GB-763VTag:Fc
Source (Host):HEK293Species:CyCMV
Product nameRecombinant CyCMV GB Protein, Fc-tagged
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Cat.#:GB-2601CCLTag:
Source (Host):HEK293Species:CMV
Product nameRecombinant CMV GB cell lysate
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Cat.#:GB-8HTag:
Source (Host):Species:Human
Product nameHuman haemoglobin Reference Standard
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gB Related Gene Family

IL