GNAL
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Official Full Name
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -
Synonyms
GNAL;guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type;guanine nucleotide-binding protein G(olf) subunit alpha;Adenylate cyclase stimulating G alpha protein, olfactory type;Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type;Guanine nucleotide binding protein G(olf) subunit alpha;adenylate cyclase-stimulating G alpha protein, olfactory type;guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory typ
Recombinant Proteins
- Zebrafish
- Chicken
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- HEK293
- His
- GST
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GNAL-1728Z | Recombinant Zebrafish GNAL | Mammalian Cells | Zebrafish | His |
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| GNAL-1870C | Recombinant Chicken GNAL | Mammalian Cells | Chicken | His |
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| GNAL-45H | Recombinant Human GNAL protein, GST-tagged | Wheat Germ | Human | GST | 1-458 a.a. |
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| GNAL-46H | Recombinant Human GNAL protein, GST-tagged | Wheat Germ | Human | GST | 359-458 a.a. |
|
| GNAL-7017M | Recombinant Mouse GNAL Protein | Mammalian Cells | Mouse | His |
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| GNAL-3759M | Recombinant Mouse GNAL Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| GNAL-3759M-B | Recombinant Mouse GNAL Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GNAL involved in several pathways and played different roles in them. We selected most pathways GNAL participated on our site, such as Calcium signaling pathway,Dopaminergic synapse,Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | STIM1A,GRIN2C,NTSR1,MYLK4,ERBB4,PLCB2,PDE1C,CALML5,CAMK4,ADRA1BB |
| Olfactory transduction | OLFR502,OLFR958,OLFR11,CALML5,CALM4,CLCA1,OR2K2,OR13A1,OR4C12,OR2C1 |
| Amoebiasis | PRKCB,ACTN2,COL1A1,SERPINB1C,VCL,RAB5B,COL4A6,COL5A1,COL4A1,PLCB4 |
| Chagas disease (American trypanosomiasis) | FOS,IRAK1,CD3G,C1QB,GNAI2,PIK3CG,PLCB1,CD3D,MAPK11,MAPK12 |
| Dopaminergic synapse | SLC18A2,GNG2,PRKCG,CAMK2A,PRKCB,KIF5C,GNB4,PPP2R1A,GNG13,MAPK8 |
| Parkinsons disease | NDUFB2,SLC18A2,ATP5A1,GNAI1,NDUFS1,NDUFA8,UBB,NDUFB8,Casp3,UQCR10 |
Protein Function
GNAL has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,G-protein coupled receptor binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAL itself. We selected most functions GNAL had, and list some proteins which have the same functions with GNAL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein beta/gamma-subunit complex binding | GNAI3,GNA11B,CETN2,GNAI2,GNA13,GNA11,GNAZ,GNA12A,PIK3R5,GNA13B |
| G-protein coupled receptor binding | SAA1,GNAV1,POMC,S1PR1,GNA15.4,HSPA1A,GNA11B,UCN3L,APLN,HSPA8 |
| metal ion binding | NME2,ZNHIT3,NT5C2B,SUV39H1A,ALOX8,CA15B,ZIC5,TGM2,ZNF625,NUBP2 |
| signal transducer activity | STAT2,TAAR7D,DRD1A,PLCB4,CHKA,CCR9A,VMN1R47,SH2B1,RGS11,JUP |
| GTPase activity | EFTUD1,GNAZ,GTPBP5,ARF1,RRAS2,SRPR,RAB18B,EEF1A1B,ATL3,TUBA3D |
| GTP binding | DRG1,RAB5AB,RRAGCA,RAB18,AK4,RAB14,REM1,ARL10,RAB39B,GSPT2 |
Interacting Protein
GNAL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAL here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAL.
Haus1;BABAM1;SPATA2;USP3;15-deoxy-delta(12,14
Resources
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References
- Ziegan, J; Wittstock, M; et al. Novel GNAL Mutations in Two German Patients With Sporadic Dystonia. MOVEMENT DISORDERS 29:1833-1834(2014).
- Dauer, W; et al. Inherited Isolated Dystonia: Clinical Genetics and Gene Function. NEUROTHERAPEUTICS 11:807-816(2014).
