Recombinant Human IL17RA protein, His-tagged IL17RA-1741H

Recombinant Human IL17RA protein, His-tagged

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Cat.No. : IL17RA-1741H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL17RA aa. (Pro377~Phe534 (Accession # Q96F46)) fused with N-terminal His tag was produced in E. coli cells.
Description : Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 22kDa as determined by SDS-PAGE reducing conditions.
Protein length : Pro377~Phe534 (Accession # Q96F46)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH 7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
SDS-PAGE :

Gene Name : IL17RA interleukin 17 receptor A [ Homo sapiens (human) ]
Official Symbol : IL17RA
Synonyms : IL17RA; interleukin 17 receptor A; CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R; interleukin-17 receptor A; IL-17 receptor A
Gene ID : 23765
mRNA Refseq : NM_001289905.1
Protein Refseq : NP_001276834.1
UniProt ID : Q96F46
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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