IL17RC Protein


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Official Full Name interleukin 17 receptor C
Background This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
Synonyms IL17RC; interleukin 17 receptor C; interleukin-17 receptor C; IL17 RL; IL 17 receptor C; IL 17RC; IL 17RL; IL17 receptor C; IL17F receptor; IL17RL; Interleukin 17 receptor homolog; Interleukin 17 receptor like; Interleukin 17 receptor like protein; IL-17RL; IL17Rhom; zcytoR14; IL-17 receptor C; interleukin-17 receptor homolog; interleukin-17 receptor-like protein; IL17-RL
    • Species :
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Insect Cell
    • Mammalian cells
    • Tag :
    • Fc
    • Fc/Avi
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL17RC-249H Active Recombinant Human IL17RC protein, Fc-tagged HEK293 Fc Inquiry
    Human IL17RC-423H Active Recombinant Human IL17RC Protein, Fc-tagged HEK293 Fc Inquiry
    Human IL17RC-641H Active Recombinant Human Interleukin 17 Receptor C, HIgG1 Fc-tagged, mutant CHO Fc Inquiry
    Human IL17RC-645H Active Recombinant Human Interleukin 17 Receptor C, HIgG1 Fc-tagged CHO Fc Inquiry
    Human IL17RC-786H Active Recombinant Human IL17RC Protein, His-tagged Mammalian cells His Inquiry
    Mouse Il17rc-294M Active Recombinant Mouse Il17rc, His-tagged Mammalian cells His Inquiry
    Mouse Il17rc-5648M Active Recombinant Mouse Interleukin 17 receptor C, His-tagged Mammalian cells His Inquiry
    Human IL17RC-14159H Recombinant Human IL17RC, His-tagged E.coli His Inquiry
    Human IL17RC-596H Recombinant Human IL17RC protein, His-tagged E.coli His Inquiry
    Human IL17RC-741H Recombinant Human IL17RC, His tagged Insect Cell His Inquiry
    Mouse Il17rc-7986M Recombinant Mouse Il17rc protein, His-tagged E.coli His Inquiry
    Human IL17RC-1611HCL Recombinant Human IL17RC cell lysate Human Cell N/A Inquiry
    Human IL17RC-494HCL Recombinant Human IL17RC cell lysate Insect Cell N/A Inquiry
    Human IL17RC-1865H Recombinant Human IL17RC protein, Fc & Avi-tagged, Biotinylated HEK293 Fc/Avi Inquiry
    Human IL17RC-3559H Recombinant Human IL17RC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Mouse Il17rc-3501M Recombinant Mouse Il17rc Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    IL17RC involved in several pathways and played different roles in them. We selected most pathways IL17RC participated on our site, such as IL17 signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IL17 signaling pathway IL17F; TRAF3IP2; IL17RE; IL17RC; IL17C

    IL17RC has several biochemical functions, for example, interleukin-17 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RC itself. We selected most functions IL17RC had, and list some proteins which have the same functions with IL17RC. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-17 receptor activity IL17RE; IL17RC; IL17RD; IL17RB; IL17RA

    IL17RC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RC here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RC.

    Elain, G; Jeanneau, K; et al. The Selective Anti-IL17A Monoclonal Antibody Secukinumab ( AIN457) Attenuates IL17A-Induced Levels of IL6 in Human Astrocytes. GLIA 62:725-735(2014).
    Hecker, M; Paap, BK; et al. Reassessment of Blood Gene Expression Markers for the Prognosis of Relapsing-Remitting Multiple Sclerosis. PLOS ONE 6:-(2011).

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