Recombinant Mouse Il17rc protein, His-tagged

Cat.No. : Il17rc-7986M
Product Overview : Recombinant Mouse Il17rc aa. (Arg73-Phe330 (Accession # Q8K4C2)) fused with N-terminal His tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 30.1kDa
Protein length : Arg73-Phe330 (Accession # Q8K4C2)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 5.4.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Il17rc interleukin 17 receptor C [ Mus musculus (house mouse) ]
Official Symbol : Il17rc
Synonyms : Il17rc; interleukin 17 receptor C; Il17rl; Gm19850; IL-17RC; IL17-RC; IL17-RL; 1110025H02Rik; interleukin-17 receptor C; IL-17 receptor C; IL-17RL; interleukin-17 receptor-like protein; zcytoR14
Gene ID : 171095
mRNA Refseq : NM_134159.4
Protein Refseq : NP_598920.3
UniProt ID : Q8K4C2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What experimental strategies are employed to investigate the crosstalk between IL17RC and other immune receptors or cytokine pathways? 06/15/2022

Co-stimulation assays, co-immunoprecipitation, and gene expression analysis reveal IL17RC's interplay with other immune pathways.

How are structural biology approaches, such as X-ray crystallography or cryo-electron microscopy, used to understand IL17RC's interaction with its ligands? 02/02/2022

Structural studies provide insights into IL17RC's binding interface with ligands, aiding in understanding cytokine-receptor interactions.

What methodologies are used to assess the impact of IL17RC inhibition on immune cell differentiation, migration, and cytokine production? 08/11/2021

In vitro cell migration assays, cytokine profiling, and adoptive transfer experiments investigate IL17RC's impact on immune cell functions.

Can you elaborate on the methods used to investigate IL17RC's contribution to autoimmune diseases, considering its involvement in IL17-mediated inflammation? 04/15/2021

Animal models, patient-derived cells, and genetic association studies explore IL17RC's involvement in autoimmune disorders.

Could you explain how genetic and pharmacological manipulation of IL17RC expression or function in animal models helps elucidate its role in tissue-specific inflammation? 05/26/2020

Conditional knockout models, adoptive transfer experiments, and tissue-specific inflammation assays unveil IL17RC's role in disease contexts.

How are patient-derived samples and clinical data integrated into experimental research to investigate the relevance of IL17RC in human diseases? 11/23/2019

Biomarker analysis, patient stratification, and correlation studies validate the clinical relevance of IL17RC in human diseases.

How do researchers study the potential of targeting IL17RC as a therapeutic strategy in inflammatory and autoimmune conditions? 05/04/2018

Preclinical models, therapeutic antibodies, and disease amelioration studies assess IL17RC as a target for immune-mediated disorders.

What cellular and molecular assays are utilized to unravel the downstream signaling cascades triggered by IL17RC activation and their impact on immune responses? 11/23/2017

Phosphorylation assays, reporter gene assays, and CRISPR screens dissect IL17RC-mediated signaling events and immune outcomes.

What experimental techniques are employed to study the expression and localization of IL17RC in different immune and non-immune cell types? 09/29/2017

Immunofluorescence, flow cytometry, and single-cell RNA sequencing determine IL17RC expression profiles in diverse cell populations.

How do researchers experimentally distinguish the roles of IL17RC in specific IL17 cytokine signaling pathways? 07/06/2017

Perturbation studies, siRNA knockdown, and gene editing differentiate IL17RC's roles in distinct IL17 cytokine pathways.

Customer Reviews (3)

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Reviews
12/11/2022

    High purity. -

    06/19/2022

      Suitable for signaling studies. -

      06/11/2021

        Effective in neutrophil activation. -

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