Active Recombinant Human IL17RC protein, Fc & Avi-tagged, Biotinylated

Cat.No. : IL17RC-1865H
Product Overview : Recombinant Human IL17RC protein(NP_703190.2)(Leu 21 - His 465), fused with Fc tag and Avi tag, was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : Fc & Avi
Form : PBS, pH7.4
Bio-activity : Immobilized Human IL17A, Tag Free at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-17 RC, Fc,Avitag with a linear range of 0.01-0.156 μg/mL.
Molecular Mass : 77.6 kDa
Protein Length : Leu 21 - His 465
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL17RC interleukin 17 receptor C [ Homo sapiens ]
Official Symbol : IL17RC
Synonyms : IL17RC; interleukin 17 receptor C; interleukin-17 receptor C; IL17 RL; IL-17RL; IL17Rhom; zcytoR14; IL17F receptor; IL-17 receptor C; interleukin-17 receptor homolog; interleukin-17 receptor-like protein; IL17RL; IL17-RL; FLJ95963; FLJ96005; MGC10763;
Gene ID : 84818
mRNA Refseq : NM_001203263
Protein Refseq : NP_001190192
MIM : 610925
UniProt ID : Q8NAC3

Products Types

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◆ Lysates
IL17RC-494HCL Recombinant Human IL17RC cell lysate +Inquiry
IL17RC-1611HCL Recombinant Human IL17RC cell lysate +Inquiry

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Related Gene

IL10 IL10RA IL10RB IL11 IL11RA Il11ra1 IL12 IL12A IL12B IL12RB1 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17B Il17c IL17D Il17f IL17RA IL17RD IL18 IL18BP IL18R1 IL18RAP Il19 Il1a IL1B IL1F10 IL1R1 Il1r2 IL1RAP IL1RAPL1 IL1RAPL2 IL1RL1 IL1RL2 Il1rn IL2 Il20 IL20RA IL21 IL21R IL22 IL22RA1 IL22RA2 IL23A IL24 Il25 IL27 IL27RA IL28A Il28b IL29 IL2RA IL2RB Il2rg IL3 IL31 IL32 Il33 Il34 IL3RA IL4 IL4R Il4ra Il5 IL5RA Il6 IL6R Il6ra IL6ST Il7 IL7R IL8 IL9 IL36A Il12rb2 IL17RB IL23R IL26 IL31RA IL36B IL36G IL36RN IL37 IL9R IL17RC IL17RE IL28RA IL4I1 IL20RB Il11ra2 IL7RA Il23a&Il12b

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

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Q&As (10)

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What experimental strategies are employed to investigate the crosstalk between IL17RC and other immune receptors or cytokine pathways? 06/15/2022

Co-stimulation assays, co-immunoprecipitation, and gene expression analysis reveal IL17RC's interplay with other immune pathways.

How are structural biology approaches, such as X-ray crystallography or cryo-electron microscopy, used to understand IL17RC's interaction with its ligands? 02/02/2022

Structural studies provide insights into IL17RC's binding interface with ligands, aiding in understanding cytokine-receptor interactions.

What methodologies are used to assess the impact of IL17RC inhibition on immune cell differentiation, migration, and cytokine production? 08/11/2021

In vitro cell migration assays, cytokine profiling, and adoptive transfer experiments investigate IL17RC's impact on immune cell functions.

Can you elaborate on the methods used to investigate IL17RC's contribution to autoimmune diseases, considering its involvement in IL17-mediated inflammation? 04/15/2021

Animal models, patient-derived cells, and genetic association studies explore IL17RC's involvement in autoimmune disorders.

Could you explain how genetic and pharmacological manipulation of IL17RC expression or function in animal models helps elucidate its role in tissue-specific inflammation? 05/26/2020

Conditional knockout models, adoptive transfer experiments, and tissue-specific inflammation assays unveil IL17RC's role in disease contexts.

How are patient-derived samples and clinical data integrated into experimental research to investigate the relevance of IL17RC in human diseases? 11/23/2019

Biomarker analysis, patient stratification, and correlation studies validate the clinical relevance of IL17RC in human diseases.

How do researchers study the potential of targeting IL17RC as a therapeutic strategy in inflammatory and autoimmune conditions? 05/04/2018

Preclinical models, therapeutic antibodies, and disease amelioration studies assess IL17RC as a target for immune-mediated disorders.

What cellular and molecular assays are utilized to unravel the downstream signaling cascades triggered by IL17RC activation and their impact on immune responses? 11/23/2017

Phosphorylation assays, reporter gene assays, and CRISPR screens dissect IL17RC-mediated signaling events and immune outcomes.

What experimental techniques are employed to study the expression and localization of IL17RC in different immune and non-immune cell types? 09/29/2017

Immunofluorescence, flow cytometry, and single-cell RNA sequencing determine IL17RC expression profiles in diverse cell populations.

How do researchers experimentally distinguish the roles of IL17RC in specific IL17 cytokine signaling pathways? 07/06/2017

Perturbation studies, siRNA knockdown, and gene editing differentiate IL17RC's roles in distinct IL17 cytokine pathways.

Customer Reviews (3)

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Reviews
12/11/2022

    High purity. -

    06/19/2022

      Suitable for signaling studies. -

      06/11/2021

        Effective in neutrophil activation. -

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