IL32
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Official Full Name
interleukin 32 -
Overview
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. -
Synonyms
IL32;interleukin 32;NK4;TAIF;TAIFa;TAIFb;TAIFc;TAIFd;IL-32beta;IL-32alpha;IL-32delta;IL-32gamma;interleukin-32;OTTHUMP00000236040;OTTHUMP00000236041;OTTHUMP00000236042;OTTHUMP00000236043;OTTHUMP00000236044;OTTHUMP00000236045;OTTHUMP00000236046;OTTHUMP00000236047;OTTHUMP00000236048;OTTHUMP00000236049;OTTHUMP00000236050;OTTHUMP00000236051;OTTHUMP00000236052;OTTHUMP00000236053;OTTHUMP00000236054;interleukin-32 theta;natural killer cells protein 4;natural killer cell transcript 4;tumor necrosis factor alpha-inducing factor
Recombinant Proteins
- Human
- HEK293
- E.coli
- Human Cells
- Mouse
- Yeast
- Wheat Germ
- Mammalian Cells
- In Vitro Cell Free System
- His
- Non
- GST
- DDK
- Myc
- SUMO
Involved Pathway
IL32 involved in several pathways and played different roles in them. We selected most pathways IL32 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL32 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IL32 has several biochemical functions, for example, cytokine activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL32 itself. We selected most functions IL32 had, and list some proteins which have the same functions with IL32. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IL17A/F3,IFNB1,IL15,IL1RN,GDF9,IFNA14,IL4,GM13285,IL34,IL16 |
| protein binding | SNRNP27,CD79B,CCDC141,MED4,GDNF,SOCS3,EEF1A1,CSTF3,C10orf137,C19orf73 |
Interacting Protein
IL32 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL32 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL32.
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Resources
Research Area
Inflammatory MediatorsNegative Regulators of the Jak/STAT Pathway
Receptors in the Jak/STAT Pathway
T Cell Cytokine Signaling
Other Interleukins & Receptors
Related Services
Related Products
References
