IL32

  • Official Full Name

    interleukin 32

  • Background

    This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Synonyms

    IL32; interleukin 32; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma; interleukin-32; OTTHUMP00000236040; OTTHUMP00000236041; OTTHUMP00000236042; OTTHUMP00000236043; OTTHUMP00000236044; OTTHUMP00000236045; OTTHUMP00000236046; OTTHUMP00000236047; OTTHUMP00000236048; OTTHUMP00000236049; OTTHUMP00000236050; OTTHUMP00000236051; OTTHUMP00000236052; OTTHUMP00000236053; OTTHUMP00000236054; interleukin-32 theta; natural killer cells protein 4; natural killer cell transcript 4; tumor necrosis factor alpha-inducing factor;
    • Type:
    • Antibody
    • Recombinant Proteins
    • ELISA Kit
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human cells
    • Human Cells
    • Mouse
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • GST
    • His
    • His(C
    • ter)
    • sumostar
    • Myc
    • DDK
    • Myc|DDK
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DMABT-H19213 Mouse Anti-IL32 Monoclonal Antibody Mouse Biotin
    Human IL32-301H Recombinant Human Interleukin 32 E.coli N/A
    Human CKERS-IL32-141H Human Interleukin 32, IL32 ELISA Kit N/A
    Human IL32-419H Active Recombinant Human IL32 E.coli N/A
    Human IL32-2743HCL Recombinant Human IL32 cell lysate Human Cell N/A
    Human IL32-1921H Recombinant Human IL32 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IL32-640H Active Recombinant Human IL32 E.coli N/A
    Human IL32-022H Recombinant Human IL-32 Protein, His-tagged E.coli His
    Human IL32-156H Recombinant Human IL32, His tagged Human Cell His
    Human IL32-151H Recombinant Human IL32 Protein, His-tagged Human Cells His
    Human IL32-190H Recombinant Active Human IL32 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL32-00H Recombinant Human IL32 Protein, His-tagged E.coli His
    Human IL32-108H Recombinant Human Lnterleukin 32, His-tagged E.coli His
    Human IL32-3824H Recombinant Human IL32 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL32-5189H Recombinant Human IL32 Protein, GST-tagged Wheat Germ GST
    Human IL32-151H Recombinant Human IL32 Protein, His-tagged Human cells His
    Human IL32-6150H Recombinant Human IL32 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL32-1678H Recombinant Human IL32 Protein, His&GST-tagged E.coli N-His&GST
    Human IL32-4328H Recombinant Human IL32 protein, His-sumostar-tagged Yeast His-sumostar
    Human IL32-173H Recombinant Human IL-32α Protein E.coli
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL32 Related Research Area

    IL32 involved in several pathways and played different roles in them. We selected most pathways IL32 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL32 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    IL32 has several biochemical functions, for example, cytokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL32 itself. We selected most functions IL32 had, and list some proteins which have the same functions with IL32. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityIFNA5;TNFRSF11B;CCL19A.1;IL21;Ifna15;IL33;IL28A;TNFSF15;CCL38A.4
    protein bindingCSNK2A2;FAM103A1;GNAI3;C6orf226;BCAP31;ZNF511;DNAIC2;ARPC2;PRSS21

    IL32 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL32 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL32.

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    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    Can recombinant IL32 be used to treat autoimmune diseases? 12/06/2022

    At present, research is ongoing, and IL32 is considered to have the potential to treat autoimmune diseases, but further clinical validation is required.

    What is IL32? 05/21/2022

    IL32, a protein of human origin, is an interferon-induced cytokine with a variety of biological functions.

    What is the progress of IL32 in clinical trials? 04/09/2022

    IL32 is in clinical trials and will take time to evaluate its safety and efficacy.

    Is recombinant IL32 associated with inflammation? 12/19/2021

    IL32 induce and regulate inflammatory response and participate in immune and inflammatory processes.

    Can IL32 improve immunity? 06/28/2019

    Can enhance the activity and function of immune cells, thereby improving the body immunity.

    What are the side effects of IL32? 01/11/2019

    So far, there have been no clear reports of side effects of IL32, but attention should be paid to reasonable dosage and method of use when using it.

    Customer Reviews (3)

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    Reviews
    12/13/2022

      IL-32 has good structural stability under suitable storage conditions, which can maintain its structural integrity and functional activity, and the preservation and stability are very important in the process of production and use. -

      05/20/2022

        Because the expression and function of IL-32 can vary across subtypes and shear variants, methods of producing IL-32 need to take into account the needs of specific subtypes to meet customized production needs. -

        10/26/2019

          Through proper recombination technology and expression construction, the produced IL-32 can maintain good biological activity and function, and can play its immunomodulatory, anti-tumor, anti-inflammatory and antiviral effects. -

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