| Cat.No. : |
IL32-108H
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant human Interleukin 32, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography,19.1 kDa (168aa). |
| Description : |
Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNFα and IL8 in THP1 cells, and activates typical cytokine signaling pathways involving NFκB and p38. IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton. |
| Sequences of amino acids : |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK |
| Formulation : |
Liquid. In20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol |
| Purity : |
> 95% by SDS - PAGE |
| Concentration : |
1 mg/ml (determined byBradford assay) |
| Storage : |
Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
