jun
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  • Official Full Name
  • jun proto-oncogene
  • Background
  • Transcription factor AP-1; JUN; AP-1; AP1; c-Jun; jun proto-oncogene; p39; jun oncogene; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog
  • Synonyms
  • JUN; jun proto-oncogene; jun oncogene ,v jun avian sarcoma virus 17 oncogene homolog ,v jun sarcoma virus 17 oncogene homolog (avian); transcription factor AP-1; AP 1; c Jun; Activator Protein 1; AP 1; AP1; cJun; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN; Jun oncogene; JUN protein; Jun proto oncogene; JUN_HUMAN; JUNC; Oncogene JUN; p39; Proto oncogene c jun; Proto oncogene cJun; Proto-oncogene c-jun; Transcription Factor AP 1; Transcription factor AP-1; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog (avian); V-jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; p39; jun oncogene; OTTHUMP00000010036; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog; AP1; AP-1; c-Jun
Cat.#:JUN-1027HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Jun Oncogene
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Cat.#:JUN-20HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human jun oncogene, His-tagged
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Cat.#:JUN-105HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human JUN, His-tagged
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Cat.#:JUN-18HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human JUN protein, GST-tagged
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Cat.#:JUN-27752THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN
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Cat.#:JUN-291HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
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Cat.#:JUN-292HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
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Cat.#:JUN-4856HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Proto-Oncogene, GST-tagged
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Cat.#:JUN-646HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Oncogene, GST-tagged
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Cat.#:JUN-792HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun, His-tagged, 27.3 kDa (261 aa)
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Cat.#:JUN-8483HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN, His-tagged
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Cat.#:JUN-8438MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse JUN Protein
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Cat.#:JUN-3146RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat JUN Protein
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Cat.#:JUN-2335RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey JUN Protein, His-tagged
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Cat.#:JUN-2945CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken JUN
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Cat.#:JUN-10349ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish JUN
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Cat.#:JUN-5095HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human JUN 293 Cell Lysate
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Involved Pathway

JUN involved in several pathways and played different roles in them. We selected most pathways JUN participated on our site, such as AGE/RAGE pathway, ATF-2 transcription factor network, Activated TLR4 signalling, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
AGE/RAGE pathway
CHUK; EGFR; TIRAP; DIAPH1; ATF2; MMP13; LGALS3; JAK2; DDOST; MAPK14
ATF-2 transcription factor network
MAPK14; JUNB; JUND; DUSP5; RUVBL2; CREB1; KCNA3; CBFB; DUSP10; JDP2
Activated TLR4 signalling
DUSP3; CREB1; DUSP6; APPB; APPA; AGER; PELI3; DUSP7; SAA1; DHX9
Activation of the AP-1 family of transcription factors
JUN; MAPK14; ATF2
AhR pathway
CYP1B1; FLG; NQO1; CDKN1B; CYP1A2; JUN; EGFR; CDKN1A; AHR; CYP1A1
Amphetamine addiction
GRIN2C; CREB3L2; PPP3CC; GRIA2; CALM1; GRIN3B; PPP3R2; SLC18A2; CAMK4; CALM3
Androgen receptor signaling pathway
RNF14; NR0B2A; PNRC1; SVILA; CTNNB2; RAD54L2; SMAD3B; GNB2L1; PIAS3; STUB1
Apoptosis
PRKAR2A; CASP4; TNFRSF1A; CASP8; BADB; TNFRSF10D; IL1RAP; VIML; PLEC; BIRC3

Protein Function

JUN has several biochemical functions, for example, DNA binding, GTPase activator activity, HMG box domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUN itself. We selected most functions JUN had, and list some proteins which have the same functions with JUN. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein SMARCB1A; PAX7A; CXXC1A; ZNF222; H2AFV; PAX1A; EF1; H1M; PLSCR1; HIST1H3H
Function GTPase activator activity
Related Protein ASAP2A; CDC42EP1B; CDC42EP3; DEPDC1B; ALS2CL; OPHN1; TBC1D19; GDI1; CDC42EP5; RGS2
Function HMG box domain binding
Related Protein PAX3; JUN; SP1; DLX5; GATA3; EGR2; POU3F3; UTF1; HOXC4; MEOX1
Function R-SMAD binding
Related Protein MYOCD; PPM1A; ZEB2; SMURF1; RANBP3; PMEPA1; TRIM33; PAX6; SMAD6; MEN1
Function RNA polymerase II activating transcription factor binding
Related Protein SMAD3; RB1; EP300; HIPK2; ATF2; TP53BP1; ISL1; T; CREBBP; CREB1
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein MITF; FEZF2; MAFB; OTX1; EN1; NKX2; ZNF460; FOXJ1; HIST2H3A; MYOG
Function RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein NR2F6; POU4F1; NR5A2; REL; CDX1; PROP1; NONO; ARX; BACH2; ZBTB16
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein EPAS1; FOXI3A; JUND; FOXB1A; ELF2; SOX9A; ATF4; FOXO1B; NFIB; FLI1B
Function cAMP response element binding
Related Protein CREB3L2; ATF2; ATF6; E4F1; CREB3L1; JUN; CREB1; CREB3L3L; HMGA2; CREB3L4
Function chromatin binding
Related Protein ADNP; GATA2; DMRT1; CREBBP; PPARG; CRX; CHD7; MAZ; DLX2; TOX
Function enzyme binding
Related Protein NOTCH3; LDB1; CBX4; RCOR2; TAF10; UBE4B; RYR2; GOT2; PDE4D; AXIN1
Function poly(A) RNA binding
Related Protein NOP16; NXF1; LLPH; DHX30; MAGOH2; RRP9; SAMSN1; ADK; NXF2; DDX52
Function protein binding
Related Protein ITGB1; LOXL4; RAD23B; SYTL4; MKNK2; WNT3A; HSPH1; XRCC2; DCP1A; TLE2
Function transcription coactivator activity
Related Protein JUN; EDF1; GATA3; CITED2; GTF2A1L; WWC1; HTATIP2; USP16; MAML1; NFYC
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein USF1; RELA; LEF1; OLIG2; NR1H4; SRY; NKX2-5; SOX9; GLI1; SNAI2
Function transcription factor activity, sequence-specific DNA binding
Related Protein DMRT1; REST; RCOR2; GATAD2B; ZNF668; ZNF773; HSFY1; FOXC2; ATF3; E2F1
Function transcription factor binding
Related Protein LCOR; HEY1; PPP1R13B; PSMD10; HES6; PAXBP1; PPARGC1A; NIF3L1; FHL2; EGR1
Function transcription regulatory region DNA binding
Related Protein RREB1; NKX3-1; SNCA; OVOL2; NKX2-5; DHX36; NFE2L2; TAF9; TFE3; HMGB2
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein MITF; FOXK2; ETV4; NR3C1; SIX4; FUBP3; NFIA; MAFB; NEUROD6; JUNB
Function transcriptional activator activity, RNA polymerase II transcription factor binding
Related Protein FOXH1; SOX10; NFE2L1; CLOCK; KLF4; NKX2-5; PITX1; GBX2; MIXL1; JUN

Interacting Protein

JUN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUN here. Most of them are supplied by our site. Hope this information will be useful for your research of JUN.
FOS

JUN Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Rodriguez, AM; Davila, MP; et al. Tumor Necrosis Factor alpha Phosphorylates c-Jun N-Terminal Kinase in Stallion Spermatozoa: Effect of Cryopreservation. JOURNAL OF EQUINE VETERINARY SCIENCE 35:206-212(2015).