Lcn2

  • Official Full Name

    lipocalin 2

  • Synonyms

    LCN2; lipocalin 2; 24p3; MSFI; NGAL; neutrophil gelatinase-associated lipocalin; p25; lipocalin-2; oncogene 24p3; siderocalin LCN2; migration-stimulating factor inhibitor; 25 kDa alpha-2-microglobulin-related subunit of MMP-9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Dog
  • Gln21-Gly198
  • Human
  • Mouse
  • Pig
  • Rat
  • Baculovirus-Infected Sf9 Cells
  • C-His
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293F
  • HEK293T
  • Human Cell
  • Human Neutrophil
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • P.pastoris
  • Fc
  • Flag
  • GFP
  • GST
  • His
  • Avi
  • T7
  • Myc
  • DDK
  • Non
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LCN2-4H Active Recombinant Human Neutrophil gela-tinase-associated lipocalin E.coli Non
Human LCN2-106H Recombinant Human Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 P.pastoris Non
Human LCN2-29122TH Recombinant Human LCN2, FLAG-tagged HEK293 Flag 198 amino acids
Human LCN2-042H Recombinant Human LCN2 protein, His-tagged HEK293 His Gln21-Gly198
Human LCN2-5244H Recombinant Human LCN2 Protein, GST-tagged E.coli GST 19-198
Human LCN2-44H Recombinant Human Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2,His-tagged E.coli His
Human LCN2-797H Recombinant Human LCN2 protein(Met1-Gly198), His-tagged HEK293 His Met1-Gly198
Human LCN2-28594TH Recombinant Human LCN2 protein E.coli Non 178
Human LCN2-29121TH Recombinant Human LCN2, His-tagged E.coli His
Human LCN2-4930H Recombinant Human Lipocalin 2 E.coli Non 21-198
Human LCN2-3409H Recombinant Human Lipocalin 2, His-tagged E.coli His
Human LCN2-2895HCL Recombinant Human LCN2 cell lysate Human Cell Non
Human LCN2-1279H Recombinant Human LCN2 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Human LCN2-4424H Recombinant Human LCN2 Protein (Gln21-Gly198), C-His tagged Mammalian cells His Gln21-Gly198
Human LCN2-342H Recombinant Human LCN2 Protein, MYC/DDK-tagged HEK293 Myc&DDK
Human LCN2-001H Recombinant Human LCN2 Protein, GST-tagged E.coli GST 19-198
Human LCN2-364H Recombinant Human LCN2 Protein, His-tagged HEK293 His 198
Human LCN2-1026H Active Recombinant Human NGAL Protein E.coli His
Human LCN2-19H Active Human NGAL Reference Standard Non
Human LCN2-1454HFL Recombinant Full Length Human LCN2 Protein, C-Flag-tagged Mammalian cells Flag
Human LCN2-2574H Active Recombinant Human LCN2 protein Baculovirus-Infected Sf9 Cells Non Gln21-Gly198
Human LCN2-384H Native Human Lipocalin-2 Human Neutrophil Non
Human LCN2-4423H Recombinant Human LCN2 Protein (Gln21-Gly198), C-His tagged E.coli His Gln21-Gly198
Human LCN2-0026H Recombinant Human LCN2 Protein HEK293 cells
Human LCN2-4425H Recombinant Human LCN2 Protein (Gln21-Gly198), N-His tagged E.coli His Gln21-Gly198
Human LCN2-1279H-B Recombinant Human LCN2 Protein Pre-coupled Magnetic Beads HEK293
Human LCN2-3973H Recombinant Human LCN2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc&DDK
Human LCN2-1151H Recombinant Human LCN2 Protein, His-tagged HEK293F His Gln21-Gly198
Mouse Lcn2-2739M Active Recombinant Murine Lipocalin 2, GFP-tagged E.coli GFP
Mouse Lcn2-2156M Recombinant Mouse Lipocalin 2, FLAG-tagged HEK293 Flag 1-200
Mouse Lcn2-1007M Recombinant Mouse Lipocalin 2, His-tagged E.coli His
Mouse Lcn2-3272M Recombinant Mouse Lcn2 protein, Fc-tagged HEK293 Fc Gln21-Asn200
Mouse Lcn2-394M Recombinant Mouse Lcn2, FLAG-tagged HEK293 Flag 1-200
Mouse Lcn2-3271M Recombinant Mouse Lcn2 protein(Met1-Asn200), His-tagged HEK293 His Met1-Asn200
Mouse Lcn2-73M Recombinant Mouse Lcn2, His-tagged E.coli His
Mouse LCN2-2781MCL Recombinant Mouse LCN2 cell lysate Human Cell Non
Mouse Lcn2-1150M Recombinant Mouse Lcn2 Protein, His-tagged HEK293F His Gln21-Asn200
Mouse Lcn2-1301M Active Recombinant Mouse Lcn2 Protein, His-tagged HEK293 His Gln21-Asn200
Mouse LCN2-797M Recombinant Mouse LCN2 Protein (Met1-Asn200) HEK293 Non Met1-Asn200
Mouse Lcn2-5711M Recombinant Mouse Lcn2 Protein (Gln21-Gly198), C-His tagged Mammalian cells His Gln21-Gly198
Mouse Lcn2-5710M Recombinant Mouse Lcn2 Protein (Gln21-Asn200), C-Fc tagged Mammalian cells Fc Gln21-Asn200
Mouse Lcn2-1302M Recombinant Mouse Lcn2 Protein, MYC/DDK-tagged HEK293T Myc&DDK
Mouse Lcn2-7249M Recombinant Mouse Lcn2 Protein, His-tagged E.coli His 21-200
Mouse Lcn2-52M Mouse NGAL Reference Standard Non
Rat LCN2-3368R Recombinant Rat LCN2 Protein Mammalian Cell His
Rat Lcn2-5176R Active Recombinant Rat Lcn2 protein(Met1-Asn198), His-tagged Insect Cells His Met1-Asn198
Rat Lcn2-2157R Recombinant Rat Lipocalin 2, FLAG-Tagged HEK293 Flag 1-198
Rat Lcn2-51R Recombinant Rat Lcn2 protein, His-tagged E.coli His 21-198
Rat LCN2-538RCL Recombinant Rat LCN2 cell lysate Insect Cell Non
Rat LCN2-3024R-B Recombinant Rat LCN2 Protein Pre-coupled Magnetic Beads HEK293
Rat Lcn2-86R Rat NGAL Reference Standard Non
Rat LCN2-3024R Recombinant Rat LCN2 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Dog LCN2-6895D Recombinant Dog LCN2 protein, His-tagged E.coli His Ser23~Glu198
Gln21-Gly198 LCN2-1301C Recombinant Cynomolgus LCN2 protein, His-tagged C-His Gln21-Gly198
Pig LCN2-6896P Recombinant Pig LCN2 protein, His & T7-tagged E.coli His&T7 Thr23~Gln199
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

Lcn2 involved in several pathways and played different roles in them. We selected most pathways Lcn2 participated on our site, such as Iron uptake and transport, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with Lcn2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Iron uptake and transportCP;FLVCR1;TFA;FTH1B;SLC22A17;FTH1A;TCIRG1;LCN2;SLC46A1
Transmembrane transport of small moleculesSLC6A6A;SLC9A8;PIP;SLC4A4A;SLC26A7;SLC4A1A;ATP13A1;SLC36A2;TSC22D3

Lcn2 has several biochemical functions, for example, iron ion binding, protease binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Lcn2 itself. We selected most functions Lcn2 had, and list some proteins which have the same functions with Lcn2. You can find most of the proteins on our site.

Function Related Protein
iron ion bindingCYP46A1.4;CYP2X7;CYP1B1;SC5DL;CYP2K22;CYP2B6;HBAA1;TMEM195;MFI2
protease bindingITGA3;SRI;LRP1;CFLAR;SERPINA1E;Cstb;BRCA2;CST3;CAST
protein homodimerization activityXCL1;XDH;PEX7;TFAP2A;VEGFB;PSPH;NR6A1B;TREX1;NOS1
small molecule bindingPAEP;MUP3;PTGDSB;LCN2;RBP4L;LCN15;MUP17;AMBP;MUP20
transporter activityMIPA;PMP2;SYPL2A;SLC5A11;NUP88;SLC37A4A;ABCA13;SLC22A13;SLC2A8

Lcn2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Lcn2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Lcn2.

Research Area

Related articles

Cheng, L; Xing, H; et al. Lipocalin-2 Promotes M1 Macrophages Polarization in a Mouse Cardiac Ischaemia-Reperfusion Injury Model. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 81:31-38(2015).
Guo, P; You, JO; et al. Inhibiting Metastatic Breast Cancer Cell Migration via the Synergy of Targeted, pH-triggered siRNA Delivery and Chemokine Axis Blockade. MOLECULAR PHARMACEUTICS 11:755-765(2014).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
05/02/2022

    They have a wide range of products and can always find LCN2 we need.

    03/11/2021

      The reproducibility of LCN2 is almost 100 percent, and the results are very consistent in every experiment or application, which is an important reflection of its excellent quality.

      12/15/2019

        Catalytic activity of LCN2 is really amazing, and every time it is used, it gives an unexpected catalytic effect and its performance is impressive.

        Q&As (6)

        Ask a question
        What diseases are associated with mutations or abnormal expression of the LCN2 protein? 06/19/2022

        Mutations or abnormal expression of the LCN2 protein may be associated with a variety of diseases. For example, in hereditary kidney disease, mutations in the uNGAL gene can lead to kidney damage. In addition, in inflammatory diseases, tumors, and other diseases, the expression level of LCN2 protein may also change.

        What diseases are LCN2 protein expression levels associated with? 11/15/2020

        Studies have shown that the expression level of LCN2 protein is associated with a variety of diseases. For example, in kidney disease, expression levels of the LCN2 protein can be elevated and can be used as one of the biomarkers to assess the extent of kidney damage. In addition, in inflammatory diseases, tumors, and other diseases, the expression level of LCN2 protein can also change.

        What is the interaction between the LCN2 protein and other proteins or molecules? 07/22/2020

        The interaction between the LCN2 protein and other proteins or molecules is complex. For example, it can participate in lipid metabolism processes by interacting with lipid molecules. In addition, it can interact with other signal transduction molecules to participate in the signal transduction process.

        How can the expression level of LCN2 protein be used for disease diagnosis? 04/03/2020

        Kidney function can be assessed by measuring the level of uNGAL in urine, and to help diagnose kidney disease, etc. In addition, abnormal levels of LCN2 protein expression can also be used as an indicator to assess the risk and prognosis of other diseases.

        How is the activity of LCN2 protein regulated? 02/16/2020

        The activity of the LCN2 protein is regulated by a variety of factors. First, its expression level is regulated by gene expression. Secondly, its activity is also regulated by a variety of small molecule compounds, hormones and other substances. In addition, the LCN2 protein can also regulate its activity by interacting with other proteins.

        How does the LCN2 protein relate to other biomarkers? 06/06/2019

        LCN2 protein has some association with other biomarkers. For example, in kidney disease, expression levels of uNGAL can be used alongside traditional biomarkers such as creatinine to assess kidney function and degree of impairment. In addition, in diseases such as tumors, expression levels of the LCN2 protein may also change and be associated with other biomarkers.

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