Recombinant Human LCN2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LCN2-3973H
• Product Overview: LCN2 MS Standard C13 and N15-labeled recombinant protein (NP_005555) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 22.6 kDa
• AA Sequence: MPLGLLWLGLALLGALHAQAQDSTS DLIPAPPLSKVPLQQNFQDNQFQGK WYVVGLAGNAILREDKDPQKMYATI YELKEDKSYNVTSVLFRKKKCDYWI RTFVPGCQPGEFTLGNIKSYPGLTS YLVRVVSTNYNQHAMVFFKKVSQNR EYFKITLYGRTKELTSELKENFIRF SKSLGLPENHIVFPVPIDQCIDGTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LCN2 lipocalin 2 [ Homo sapiens (human) ]
• Official Symbol: LCN2
• Synonyms: LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); neutrophil gelatinase-associated lipocalin; 24p3; neutrophil gelatinase associated lipocalin; NGAL; oncogene 24p3; siderocalin; p25; lipocalin-2; migration-stimulating factor inhibitor; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; MSFI
• Gene ID: 3934
• mRNA Refseq: NM_005564
• Protein Refseq: NP_005555
• MIM: 600181
• UniProt ID: P80188