"LCN2" Related Products

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Recombinant Human LCN2 Protein, His-tagged

Cat.No. : LCN2-042H
Product Overview : Recombinant human LCN2 (rhLCN2) Gln21-Gly198 (Accession # NP_005555.2) fused with a C-terminal 6×his tag was produced in human HEK293 cells.
Description : This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
Source : HEK293 cells
Species : Human
Tag : His
Molecular Mass : rhLCN2, fused with 6×his tag at C-terminal and has a calculated MW of 22 kDa. The predicted N-terminal is Gln 21. DTT-reduced protein migrates as 23-25 kDa.
Endotoxin : Less than 1.0 EU per 1 µg of the rhLCN2 by the LAL method.
Purity : >95% as determined by SDS-PAGE. All lots are greater than 95% pure.
Notes : Research Use Only. Not for use in diagnostic or therapeutic procedures.
Storage : Store at -20 centigrade in lyophilized state after receipt. For long term storage, upon reconstitution rhLCN2 should be aliquot and store at -20 centigrade or -8 centigrade centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : Bulk protein in a 0.22 µm filtered solution of PBS, pH 7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization.
Gene Name : LCN2 lipocalin 2 [ Homo sapiens ]
Official Symbol : LCN2
Synonyms : LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); neutrophil gelatinase-associated lipocalin; 24p3; neutrophil gelatinase associated lipocalin; NGAL; oncogene 24p3; siderocalin; p25; lipocalin-2; migration-stimulating factor inhibitor; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; MSFI;
Gene ID : 3934
mRNA Refseq : NM_005564
Protein Refseq : NP_005555
MIM : 600181
UniProt ID : P80188

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