Recombinant Full Length Human LCN2 Protein, C-Flag-tagged

• Cat.No.: LCN2-1454HFL
• Product Overview: Recombinant Full Length Human LCN2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 22.4 kDa
• AA Sequence: MPLGLLWLGLALLGALHAQAQDSTS DLIPAPPLSKVPLQQNFQDNQFQGK WYVVGLAGNAILREDKDPQK MYATIYELKEDKSYNVTSVLFRKKK CDYWIRTFVPGCQPGEFTLGNIKSY PGLTSYLVRVVSTNYNQHAM
  VFFKKVSQNREYFKITLYGRTKELT SELKENFIRFSKSLGLPENHIVFPV PIDQCIDGTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: LCN2 lipocalin 2 [ Homo sapiens (human) ]
• Official Symbol: LCN2
• Synonyms: p25; 24p3; MSFI; NGAL
• Gene ID: 3934
• mRNA Refseq: NM_005564.5
• Protein Refseq: NP_005555.2
• MIM: 600181
• UniProt ID: P80188