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Official Full Name protease, serine, 1 (trypsin 1)
Background This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.
Synonyms PRSS1; protease, serine, 1 (trypsin 1); TRY1; trypsin-1; Alpha-trypsin chain 2; Beta-trypsin; Cationic trypsinogen; Serine protease 1; TRY1_HUMAN; Trypsin I; trypsinogen 1; trypsinogen A; digestive zymogen; nonfunctional trypsin 1; TRP1; TRY4; TRYP1
    • Species :
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Human Pancreas
    • Mammalian Cell
    • NS0
    • Yeast
    • Tag :
    • Fc
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PRSS1-1047H Recombinant Human PRSS1, His-tagged NS0 His
    Human PRSS1-273H Recombinant Human PRSS1 Protein, His-tagged E.coli His
    Human PRSS1-2806HCL Recombinant Human PRSS1 293 Cell Lysate HEK293 N/A
    Human PRSS1-30745TH Native Human PRSS1 Human Pancreas N/A
    Human PRSS1-516H Recombinant Human PRSS1 Protein, His-tagged NS0 His
    Human PRSS1-5894H Recombinant Human PRSS1 protein, Fc/His-tagged HEK293 Fc/His
    Rat PRSS1-1494R Recombinant Rat PRSS1 Protein (24–246 aa), His-tagged Yeast His
    Rat Prss1-3466R Recombinant Rat Prss1, His-tagged E.Coli or Yeast His
    Rat PRSS1-4737R Recombinant Rat PRSS1 Protein Mammalian Cell His
    Rat PRSS1-746R Recombinant Rat PRSS1 Protein (24-246 aa), His-SUMO-tagged E.coli His/SUMO
    Rhesus Macaque PRSS1-3635R Recombinant Rhesus monkey PRSS1 Protein, His-tagged Mammalian Cell His

    prss1 involved in several pathways and played different roles in them. We selected most pathways prss1 participated on our site, such as Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with prss1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction TAAR14A; PTH1R; HTR1AB; GRPR; F2; HRH4; GABRD; PTGER2A; PARD3; GABRB1
    Pancreatic secretion PLA2G12B; RYR2; GNAS; CA2; AMY2A; CPA1; PLA2G2F; CCKAR; ATP1B3; PLA2G1B
    Protein digestion and absorption DPP4; SLC38A2; LOC780933; COL6A6; KCNK5; CPA2; ATP1A2; XPNPEP2; CELA2A; SLC3A2
    Influenza A SOCS3; HSPA1B; MAPK3; MAPK13; BLB1; IL18; IL33; Ifna11; IFN-a; NXT2

    prss1 has several biochemical functions, for example, metal ion binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by prss1 itself. We selected most functions prss1 had, and list some proteins which have the same functions with prss1. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding PNKD; SLC8A1; POLK; RNF34B; CYP3A25; ZFP207; IRF2BP2A; NCS1B; DGKD; TRIM8A
    serine-type endopeptidase activity HTRA1A; MASP2; F10; TMPRSS13B; CMA1; PRSS45; PROCA; HTRA1B; RHBDD2; KLK12

    prss1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with prss1 here. Most of them are supplied by our site. Hope this information will be useful for your research of prss1.

    GRB2; ALB; PPP2R2B; STK38L

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