Active Recombinant Human PRSS1 Protein, His-tagged
Cat.No. : | PRSS1-516H |
Product Overview : | Recombinant Human PRSS1 (Accession # NP_002760) Ala16-Ser247, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
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Source : | Mammalian cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ala16 |
Form : | Supplied as a 0.2 µm filtered solution in HCl and NaCl. |
Bio-activity : | Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2.The specific activity is >3,000 pmol/min/µg, as measured under the described conditions. |
Molecular Mass : | Recombinant Human PRSS1, His-tagged has a calculated MW of 26 kDa. In SDS-PAGE migrates as 32 kDa and 36 kDa, reducing conditions. |
Protein length : | Ala16-Ser247 |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | PRSS1 protease, serine, 1 (trypsin 1) [ Homo sapiens ] |
Official Symbol : | PRSS1 |
Synonyms : | PRSS1; protease, serine, 1 (trypsin 1); TRY1; trypsin-1; beta-trypsin; trypsinogen 1; trypsinogen A; digestive zymogen; cationic trypsinogen; nonfunctional trypsin 1; TRP1; TRY4; TRYP1; FLJ57296; MGC120175; MGC149362; DKFZp779A0837; |
Gene ID : | 5644 |
mRNA Refseq : | NM_002769 |
Protein Refseq : | NP_002760 |
MIM : | 276000 |
UniProt ID : | P07477 |
Chromosome Location : | 7q34 |
Products Types
◆ Recombinant Protein | ||
Prss1-1991R | Recombinant Rat Prss1 Protein, His-tagged | +Inquiry |
PRSS1-3925H | Recombinant Human PRSS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Prss1-1990M | Recombinant Mouse Prss1 Protein, His-tagged | +Inquiry |
PRSS1-1494R | Recombinant Rat PRSS1 Protein (24–246 aa), His-tagged | +Inquiry |
PRSS1-3453R | Recombinant Rhesus Macaque PRSS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
PRSS1-30745TH | Active Native Human Trypsin | +Inquiry |
◆ Lysates | ||
PRSS1-2806HCL | Recombinant Human PRSS1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe pharmacodynamic parameters of PRSS1 were good.
PRSS1 has very high sensitivity in Western blot and can detect low concentrations of the protein of interest.
PRSS1 has good compatibility and stability with various excipients.
Q&As (6)
Ask a questionThe structure of PRSS1 determines its ability to bind specifically to the substrate and the efficiency of the catalytic reaction. The study of its structure can help us understand its function and mechanism of action.
PRSS1 can interact with other digestive enzymes, such as stomach acid and bile, to participate in the digestive process of food.
It is primarily involved in the digestion of proteins in the digestive system, breaking them down into small peptides and amino acids.
Therapeutic strategies for PRSS1 may include supplementing or inhibiting its expression and regulating its interaction with other digestive enzymes. These methods may have potential applications in treating diseases such as pancreatitis or pancreatic cancer.
The expression of PRSS1 in the pancreas is determined by factors such as its substrate specificity and synergies with other digestive enzymes. In other organs, its expression may vary by different regulatory mechanisms.
Lack of PRSS1 may lead to protein digestion disorders, while overexpression of PRSS1 may lead to diseases such as pancreatitis or pancreatic cancer.
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