wnt5a
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  • Official Full Name
  • wingless-type MMTV integration site family, member 5A
  • Background
  • The Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transm
  • Synonyms
  • WNT5A; wingless-type MMTV integration site family, member 5A; protein Wnt-5a; hWNT5A; WNT 5A protein; WNT-5A protein
Cat.#:WNT5A-20HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WNT5A Protein, GST-tagged
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Cat.#:Wnt5a-65RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Wnt5a Protein, His-tagged
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Cat.#:WNT5A-1634HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WNT5A protein, His-tagged
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Cat.#:WNT5A-19HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human WNT5A protein
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Cat.#:WNT5A-2052HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human WNT5A, GST-tagged
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Cat.#:WNT5A-2053HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human WNT5A, MYC/DDK-tagged
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Cat.#:WNT5A-2055HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human WNT5A, GST-tagged
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Cat.#:WNT5A-206HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human WNT5A, StrepII-tagged
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Cat.#:Wnt5a-1492MTag:GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Wnt5a protein, GST-tagged
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Cat.#:WNT5A-18573MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse WNT5A Protein
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Cat.#:Wnt5a-2051MTag:N/A
Source (Host):mouse fibroblast cellsSpecies:Mouse
Product nameRecombinant Mouse Wingless-Related MMTV Integration Site 5A
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Cat.#:Wnt5a-2054MTag:
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Wnt5a
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Cat.#:Wnt5a-2055MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Wnt5a protein, His/GST-tagged
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Cat.#:WNT5A-6600RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat WNT5A Protein
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Cat.#:WNT5A-6450CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken WNT5A
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Cat.#:WNT5A-4899ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WNT5A
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Cat.#:WNT5A-293HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WNT5A 293 Cell Lysate
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Involved Pathway

Wnt5a involved in several pathways and played different roles in them. We selected most pathways Wnt5a participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Wnt5a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
TP53; PPARDB; BAMBIA; CAMK2B1; MAPK9; PRKCB; TBL1XR1; MAPK8B; AXIN2; MYCB
Hedgehog signaling pathway
IHH; WNT4A; WNT2B; WNT6; ZIC2A; RAB23; GSK3B; GAS1B; CSNK1DA; ZIC2B
Hippo signaling pathway
WWTR1; LLGL1; DLG3; PARD6A; SOX2; BMP7; CTNNA3; BMP4; WNT2B; BMP6
Signaling pathways regulating pluripotency of stem cells
MEIS1; FZD7; PCGF6; MAPK12; STAT3; SMAD9; FGFR2; WNT9A; FZD9; TBX3
Melanogenesis
CAMK2G; WNT8B; PRKCB; PRKACG; TYR; ADCY1B; PRKACAB; Fzd4; WNT8A; FZD7A
HTLV-I infection
SLC25A4; CDC23; KAT2B; RRAS; MYB; STAT5B; CALR; BUB3; CDC16; IL2RA
Pathways in cancer
FGF21; GNA11; TGFA; PRKCA; WNT7B; SOS1; COL4A1; BDKRB2; TRAF5; XIAP
Proteoglycans in cancer
MRAS; TIMP3; CAMK2D; ROCK1; MMP9; ELK1; CAV1; FZD6; COL21A1; MAP2K2
Basal cell carcinoma
WNT3A; Shh; AXIN2; FZD1; WNT7A; GLI2; FZD10; WNT8A; PTCH2; WNT8B

Protein Function

Wnt5a has several biochemical functions, for example, cytokine activity, frizzled binding, frizzled-2 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Wnt5a itself. We selected most functions Wnt5a had, and list some proteins which have the same functions with Wnt5a. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IL5; GM13278; CSF1; TGFB1; LEFTY1; GDF6; VEGFA; TNFSF15; ADIPOQ; AIMP1
Function frizzled binding
Related Protein LRP6; DVL3A; FZD7; BAMBI; WNT3; WNT6; WNT7B; ZNRF3; DVL1; WNT4B
Function frizzled-2 binding
Related Protein WNT5A; WNT3A
Function protein domain specific binding
Related Protein ITGA3; HIST1H4B; PRKCZ; CHMP1A; HMGB2; CALM3; ETV6; MPP5; HAND2; NFASC
Function receptor agonist activity
Related Protein VEGFA; WNT3A; WNT4; WNT3; GREM1; WNT10B; WNT7A; WNT1; CXCL13; GAS6
Function receptor tyrosine kinase-like orphan receptor binding
Related Protein WNT5A
Function transcription factor activity, sequence-specific DNA binding
Related Protein BSX; ATF6; TRP63; FOXO6; TRPS1; POU3F4; NR1D4A; POUV; BLF; ZNF493
Function transcription regulatory region DNA binding
Related Protein ZNF613; TAL1; MTERF3; SOX7; SMAD4; PHB; KDM1A; GRHL1; TAF9; ZFP821

Interacting Protein

Wnt5a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Wnt5a here. Most of them are supplied by our site. Hope this information will be useful for your research of Wnt5a.
FZD5

Wnt5a Related Articles

Shojima, K; Sato, A; et al. Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively. SCIENTIFIC REPORTS 5:-(2015).
Kikuchi, R; Nakamura, K; et al. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. NATURE MEDICINE 20:1464-1471(2014).

Wnt5a Related Gene Family

WNT