Active Recombinant Human Interleukin 16 IL16-485H

Active Recombinant Human Interleukin 16

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Active Recombinant Human Interleukin 16

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Cat.No. : IL16-485H Optional Service: Optional requirements on this protein
Product Overview : Recombinant H-IL-16 is comprised of 130 amino acids with a molecular weight of 13.5 kDa.
Description : Human IL-16 was originally described as Lymphocyte Chemoattractant Factor (LCF), is produced primarily by CD4(+) and CD8(+) T cells and acts as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells and Langerhans cells.
Species : Human
Source : E.coli
Form : Human IL-16 was lyophilized at 1 mg/ml in 10 mM NaP, 7.5.
Purity : Purity Greater than 95% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : The ED50 as determined by its ability to chemoattract human CD4+ T lymphocytes using a concentration range of 10-100 ng/ml, corresponding to a Specific Activity greater than 1000 IU/mg.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg"s/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 95% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence : MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
Storage : Lyophilized Interleukin-16 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL16 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
PDBrendering based on 1i16. :

Gene Name : IL16 interleukin 16 (lymphocyte chemoattractant factor) [ Homo sapiens ]
Official Symbol : IL16
Synonyms : IL16; interleukin 16 (lymphocyte chemoattractant factor); LCF; IL-16; prIL-16; FLJ16806; FLJ42735; FLJ44234; HsT19289; OTTHUMP00000190849; OTTHUMP00000190850; lymphocyte chemoattractant factor; HsT19289; Pro-interleukin-16; interleukin 16; lymphocyte chemoattractant factor
Gene ID : 3603
mRNA Refseq : NM_004513
Protein Refseq : NP_004504
MIM : 603035
UniProt ID : Q14005
Chromosome Location : 15q26.3
Function : cytokine activity; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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