Active Recombinant Chicken Interleukin 16 (Lymphocyte Chemoattractant Factor) IL16-247C

Active Recombinant Chicken Interleukin 16 (Lymphocyte Chemoattractant Factor)


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Active Recombinant Chicken Interleukin 16 (Lymphocyte Chemoattractant Factor)

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Cat.No. : IL16-247C Optional Service: Optional requirements on this protein
Product Overview : Recombinant Chicken IL-16 was expressed inYeast. MW= 12.6 kDa (120 aa).
Description : IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. IL-16 functions exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils. Also induces t-lymphocyte expression of interleukin 2 receptor. ligand for cd4.
Source : Yeast.
Formulation/ Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification : Ion-exchange chromatography.
Purity : >95% as visualized by SDS-PAGE analysis.
Bioactivity : The biological activity of recombinant chicken IL-16 was determined in a chemotaxis assay using a Boyden chamber with chicken PBMC following initial culture with IL-16. Bioactivity is typically detected starting at 78 ng/mL.
Stability And Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
PDB rendering based on 1i16. :

Gene Name : IL16 interleukin 16 (lymphocyte chemoattractant factor) [ Gallus gallus ]
Synonyms : interleukin 16 (lymphocyte chemoattractant factor); IL16;interleukin 16
Gene ID : 374270
mRNA Refseq : NM_204352.3
Protein Refseq : NP_989683.3
Chromosome Location : 10
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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