Recombinant Full Length Human IL16 Protein, C-Flag-tagged

• Cat.No.: IL16-1322HFL
• Product Overview: Recombinant Full Length Human IL16 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 66.5 kDa
• AA Sequence: MDYSFDTTAEDPWVRISDCIKNLFS PIMSENHGHMPLQPNASLNEEEGTQ GHPDGTPPKLDTANGTPKVY KSADSSTVKKGPPVAPKPAWFRQSL KGLRNRASDPRGLPDPALSTQPAPA SREHLGSHIRASSSSSSIRQ RISSFETFGSSQLPDKGAQRLSLQP SSGEAAKPLGKHEEGRFSGLLGRGA APTLVPQQPEQVLSSGSPAA SEARDPGVSESPPPGRQPNQKTLPP GPDPLLRLLSTQAEESQGPVLKMPS QRARSFPLTRSQSCETKLLD EKTSKLYSISSQVSSAVMKSLLCLP SSISCAQTPCIPKEGASPTSSSNED SAANGSAETSALDTGFSLNL SELREYTEGLTEAKEDDDGDHSSLQ SGQSVISLLSSEELKKLIEEVKVLD EATLKQLDGIHVTILHKEEG AGLGFSLAGGADLENKVITVHRVFP NGLASQEGTIQKGNEVLSINGKSLK GTTHHDALAILRQAREPRQA VIVTRKLTPEAMPDLNSSTDSAASA SAASDVSVESTAEATVCTVTLEKMS AGLGFSLEGGKGSLHGDKPL TINRIFKGAASEQSETVQPGDEILQ LGGTAMQGLTRFEAWNIIKALPDGP VTIVIRRKSLQSKETTAAGD
  STRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: IL16 interleukin 16 [ Homo sapiens (human) ]
• Official Symbol: IL16
• Synonyms: LCF; NIL16; PRIL16; prIL-16
• Gene ID: 3603
• mRNA Refseq: NM_004513.6
• Protein Refseq: NP_004504.3
• MIM: 603035
• UniProt ID: Q9UME6