CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit
| Cat.No. : | Kit-1705 |
| Product Overview : | The activation of native T cells requires two signals, the specific T cell receptor recognition of MHC/Antigen on the surface of the antigen-presenting cell (APC), and the binding of B7-1 (CD80) ligand on the APC with the CD28 receptor on the T cell surface. CD28:B7-1 interaction is an important drug target for the regulation of T cells involved in autoimmunity, inflammation, tumor recognition, and immune tolerance. |
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| Size : | 96 reactions |
| Applications : | This kit is useful for screening for inhibitors of B7-1 binding to CD28. |
| Storage : | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Products Types
| ◆ Lysates | ||
| CD28-2002MCL | Recombinant Mouse CD28 cell lysate | +Inquiry |
| CD28-2013HCL | Recombinant Human CD28 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIts unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.
Q&As (5)
Ask a questionCD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.
Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.
CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.
CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.
Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.
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