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CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit
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Cat.No. : | Kit-1712 |
Product Overview : | The activation of native T cells requires two signals, the specific T cell receptor recognition of MHC/Antigen on the surface of the antigen-presenting cell (APC), and the binding of B7-1 (CD80) ligand on the APC with the CD28 receptor on the T cell surface. Conversely, binding of CTLA4 to B7-1 on the T-cell surface results in an inhibitory signal and prevents T-cell activation. CTLA4:B7-1 interaction is an important drug target for the regulation of the host"s response to cancer. |
Size : | 96 reactions |
Applications : | This kit is useful for screening for inhibitors of B7-1 binding to CTLA4. |
Storage : | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
◆ Recombinant Protein
CTLA4-2075H | Recombinant Human CTLA4 Protein, GST-tagged | +Inquiry |
Ctla4-038M | Recombinant Mouse Ctla4 Protein, Fc-tagged | +Inquiry |
CTLA4-257H | Recombinant Human CTLA4 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
CTLA4-499H | Recombinant Human CTLA4 Protein (Met1-Phe162), HIgG1 Fc-tagged | +Inquiry |
CTLA4-4413B | Recombinant Bovine CTLA4 Protein | +Inquiry |
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◆ Lysates
CTLA4-2179MCL | Recombinant Mouse CTLA4 cell lysate | +Inquiry |
CTLA4-2526HCL | Recombinant Human CTLA4 cell lysate | +Inquiry |
CTLA4-1047CCL | Recombinant Cynomolgus CTLA4 cell lysate | +Inquiry |
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◆ Assay kits
Kit-1713 | CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit | +Inquiry |
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