HDAC8 Fluorogenic Assay Kit
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Cat.No. : | Kit-1744 |
Product Overview : | HDACs regulate cellular processes by catalyzing the hydrolysis of an acetyl group from acetyllysines in modified proteins. In the HDAC assay, fluorescent-dye molecules are attached to a peptide containing acetyllysine. Attachment to the peptide quenches the fluorescence of the dye. After treatment of the peptide with an HDAC, the reaction is mixed with a development solution that is specific for nonacetylated lysines. If the acetyl group has been removed from the lysine by the HDAC, this solution will release the dye allowing for fluorescence. Fluorescence is therefore directly related to HDAC activity. |
Size : | 96 reactions |
Applications : | Great for studying enzyme kinetics and screening small molecular inhibitors of HDAC8 for drug discovery and HTS applications. |
Storage : | 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
◆ Recombinant Protein
HDAC8-314H | Recombinant Human HDAC8 Protein | +Inquiry |
HDAC8-26H | Recombinant Human HDAC8 Protein, His-tagged | +Inquiry |
HDAC8-4650H | Recombinant Human HDAC8 Protein, GST-tagged | +Inquiry |
HDAC8-27529TH | Recombinant Human HDAC8, His-tagged | +Inquiry |
HDAC8-2818R | Recombinant Rat HDAC8 Protein | +Inquiry |
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◆ Lysates
HDAC8-537MCL | Recombinant Mouse HDAC8 cell lysate | +Inquiry |
HDAC8-691HCL | Recombinant Human HDAC8 cell lysate | +Inquiry |
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◆ Assay kits
Kit-2253 | HDAC8 Activity Fluorometric Assay Kit | +Inquiry |
Kit-1961 | HDAC8 Inhibitor Screening Assay Kit | +Inquiry |
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