Recombinant Human HDAC8 Protein, His-tagged
Cat.No. : | HDAC8-26H |
Product Overview : | Recombinant human HDAC8(2-377) protein with a C-terminal His-tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 45.3 kDa |
Protein length : | 2-377 |
Purity : | ≥85% estimated by SDS-PAGE |
Unit Definition : | One unit is the amount of enzyme required to release 1 nmol/min acetate from 100 μM acetylated p53 peptide at 37 centigrade in 25 mM Tris, pH 8.0, 137 mM NaCl, 2.7 mM KCl, and 1 mM MgCl2. |
Stability : | ≥ 6 months |
Storage : | Store it at -80 centigrade |
Storage Buffer : | 50 mM Tris, pH 7.5, with 200 mM sodium chloride 2.5 mM potassium chloride, 1 mM TCEP, 25% glycerol |
Gene Name : | HDAC8 histone deacetylase 8 [ Homo sapiens (human) ] |
Official Symbol : | HDAC8 |
Synonyms : | HDAC8; histone deacetylase 8; HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; histone deacetylase 8; histone deacetylase-like 1 |
Gene ID : | 55869 |
mRNA Refseq : | NM_001166418 |
Protein Refseq : | NP_001159890 |
MIM : | 300269 |
UniProt ID : | Q9BY41 |
Products Types
◆ Recombinant Protein | ||
HDAC8-4650H | Recombinant Human HDAC8 Protein, GST-tagged | +Inquiry |
HDAC8-125H | Recombinant Human HDAC8 Protein, His-tagged | +Inquiry |
HDAC8-314H | Active Recombinant Human HDAC8 Protein | +Inquiry |
HDAC8-2473R | Recombinant Rat HDAC8 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC8-2827H | Recombinant Human HDAC8 Protein (Met1-Val377), C-His tagged | +Inquiry |
◆ Lysates | ||
HDAC8-537MCL | Recombinant Mouse HDAC8 cell lysate | +Inquiry |
HDAC8-691HCL | Recombinant Human HDAC8 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2253 | HDAC8 Activity Fluorometric Assay Kit | +Inquiry |
Kit-1744 | HDAC8 Fluorogenic Assay Kit | +Inquiry |
Kit-1961 | HDAC8 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All HDAC8 Products
Required fields are marked with *
My Review for All HDAC8 Products
Required fields are marked with *
0
Inquiry Basket