Native Human Transferrin
Cat.No. : | TF-31158TH |
Product Overview : | Full length native Human Transferrin purified from Human plasma; amino acids 20-698, 679 amino acids, MWt 80kDa. |
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Description : | This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. |
Tissue specificity : | Expressed by the liver and secreted in plasma. |
Biological activity : | Iron Content: >= 1100 ug per gram. |
Form : | Lyophilised |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20mM Sodium phosphate, 150mM Sodium chloride, pH 7.4 |
Storage : | Shipped at 4°C. Store at -20oC. |
Sequence Similarities : | Belongs to the transferrin family.Contains 2 transferrin-like domains. |
Tag : | Non |
Protein length : | 20-698 |
Gene Name : | TF transferrin [ Homo sapiens ] |
Official Symbol : | TF |
Synonyms : | TF; transferrin; serotransferrin; PRO1557; PRO2086; |
Gene ID : | 7018 |
mRNA Refseq : | NM_001063 |
Protein Refseq : | NP_001054 |
MIM : | 190000 |
Uniprot ID : | P02787 |
Chromosome Location : | 3q21 |
Pathway : | EPHB forward signaling, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Mineral absorption, organism-specific biosystem; |
Function : | ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
Trf-148M | Recombinant Mouse Trf Protein, His-tagged | +Inquiry |
Tf-566R | Active Recombinant Rat Tf protein(Met1-Ser698), His-tagged | +Inquiry |
TF-1589C | Recombinant Canine TF protein, His-tagged | +Inquiry |
TF-11H | Recombinant Human Apo-Transferrin, Low Endotoxin, Media Grade | +Inquiry |
TF-146B | Recombinant Bovine TF Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
TF-8273H | Native Human Serum Transferrin HOLO(iron-saturated) | +Inquiry |
Tf-264R | Native Rat Transferrin | +Inquiry |
TF-132B | Native Bovine Transferrin | +Inquiry |
◆ Lysates | ||
TF-2542HCL | Recombinant Human TF cell lysate | +Inquiry |
TF-1208MCL | Recombinant Mouse TF cell lysate | +Inquiry |
TF-1554SCL | Recombinant Sus scrofa (Pig) TF cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0813 | TF (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewTheir team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.
This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.
The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.
Q&As (5)
Ask a questionYes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.
Yes, some drugs target TF proteins, especially in the treatment of cancer.
TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.
TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.
Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.
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