Recombinant Active Human FGF21 Protein, His-tagged(C-ter)
|Product Overview :
|Recombinant Active Human FGF21 Protein with His tag (C-ter) was expressed in E. coli.
- Gene Information
- Related Products
|The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq, Jul 2008]
|Determined by its ability to induce proliferation in BaF3 mouse pro-B cells transfected with human FGFRIIIc. The ED50 for this effect is < 0.4 μg/mL.
|AA Sequence :
|MHPIPDSSPLLQFGGQVRQRYLYTD DAQQTEAHLEIREDGTVGGAADQSP ESLLQLKALKPGVIQILGVKTSRFL CQRPDGALYGSLHFDPEACSFRELL LEDGYNVYQSEAHGLPLHLPGNKSP HRDPAPRGPARFLPLPGLPPALPEP PGILAPQPPDVGSSDPLSMVGPSQG RSPSYAS
|Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
|> 98% (by SDS-PAGE)
|For laboratory research only, not for drug, diagnostic or other use.
|Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
|Storage Buffer :
|PBS (pH 8.0)
|It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
|Gene Name :
|FGF21 fibroblast growth factor 21 [ Homo sapiens ]
|Official Symbol :
|FGF21; fibroblast growth factor 21; FGF-21;
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|◆ Recombinant Protein
|Active Recombinant Human FGF21 Protein (182 aa)
|Active Recombinant Mouse Fgf21 Protein (182 aa)
|Recombinant Human FGF21 Protein, His-tagged
|Recombinant Rat Fgf21 Protein, His-tagged
|Active Recombinant Human FGF21 Protein
|Recombinant Mouse FGF21 cell lysate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (7)Ask a question
FGF21 expression in adipose tissue is regulated by various factors, including peroxisome proliferator-activated receptor gamma (PPARγ) activation.
FGF21 influences lipid metabolism by promoting the utilization of fatty acids for energy, contributing to the regulation of lipid homeostasis.
FGF21 levels are being explored as potential biomarkers for metabolic health, reflecting conditions such as insulin resistance and metabolic syndrome.
Yes, FGF21 plays a role in improving insulin sensitivity, making it a potential target for interventions in insulin resistance-associated conditions.
Yes, FGF21 influences energy expenditure by promoting thermogenesis in brown adipose tissue, contributing to overall metabolic regulation.
Gender-specific differences in FGF21 levels have been reported, with some studies suggesting higher circulating FGF21 concentrations in females.
FGF21 activates signaling pathways such as the AMP-activated protein kinase (AMPK) pathway, which contributes to its metabolic effects.
Customer Reviews (3)Write a review
The manufacturer's history of producing high-quality products contributed to our trust in this protein.
Collaboration with other research groups was made easier by the product's standardized use in the scientific community.
The product's role in promoting collaboration and teamwork positively impacted the quality of our research.
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