| Description : |
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008] |
| Source : |
E. coli |
| Species : |
Mouse |
| Tag : |
His(C-ter) |
| Form : |
Powder |
| Bio-activity : |
Determined by its ability to induce proliferation in NFS-60 cells. The ED50 for this effect is < 30 ng/mL. The specific activity of recombinant mouse IL-34 is > 3.3 x 10^4 IU/mg. |
| AA Sequence : |
MNENLEIWTLTQDKECDLTGYLRGK LQYKNRLQYMKHYFPINYRIAVPYE GVLRVANITRLQKAHVSERELRYLW VLVSLNATESVMDVLLEGHPSWKYL QEVQTLLENVQRSLMDVEIGPHVEA VLSLLSTPGLSLKLVRPKALLDNCF RVMELLYCSCCKQSPILKWQDCELP RLHPHSPGSLMQCTATNVYPLSRQT PTSLPGSPSSSHGSLP |
| Endotoxin : |
Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
| Purity : |
> 98% (by SDS-PAGE) |
| Applications : |
SDS-PAGE |
| Notes : |
For laboratory research only, not for drug, diagnostic or other use. |
| Storage : |
Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Storage Buffer : |
PBS (pH 7.4) |
| Reconstitution : |
It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
