Recombinant Mouse Il34 protein, His-tagged

• Cat.No.: Il34-2098M
• Product Overview: Recombinant Mouse Il34 aa. (Asn21~Pro235 (Accession # Q8R1R4)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 26 kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Asn21~Pro235 (Accession # Q8R1R4)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 7.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Il34 interleukin 34 [ Mus musculus (house mouse) ]
• Official Symbol: Il34
• Synonyms: Naxe; NAD(P)HX epimerase; AIBP; AI-BP; ESTM37; Apoa1bp; Apoa1ip; AA087124; NAD(P)H-hydrate epimerase; apoA-I binding protein; apolipoprotein A-I binding protein; apolipoprotein A-I interacting protein
• Gene ID: 76527
• mRNA Refseq: NM_001135100.2
• Protein Refseq: NP_001128572.1
• UniProt ID: Q8R1R4

Reviews

05/10/2021

IL34 has shown good biocompatibility and safety in related experiments.

01/19/2020

When using IL34 for experiments, the experimental conditions and results are highly repeatable.

10/24/2019

Quality is stable and reliable, with no significant differences between batches.

Q&As

What is the effect of IL34 on tumor prognosis?

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments?

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor?

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing?

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system?

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34?

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.