Il34
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Official Full Name
interleukin 34
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Overview
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008] -
Synonyms
IL34; interleukin 34; IL-34; C16orf77; interleukin-34;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- Baculovirus-Insect cells
- CHO
- E.coli
- HEK293
- HEK293F
- HEK293T
- Human Cell
- Human Cells
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Yeast
- Fc
- GST
- His
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
Il34 involved in several pathways and played different roles in them. We selected most pathways Il34 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Il34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Il34 has several biochemical functions, for example, cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il34 itself. We selected most functions Il34 had, and list some proteins which have the same functions with Il34. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | BMP2B;BMP6;CMTM1;IL4;CCL19A.1;TNFSF12;LFT2;GDF5;TNFSF14 |
| growth factor activity | NTF7;FGF4;WISP3;MACC1;CXCL12;GDNFA;BMP7A;INHBA;PDGFAB |
| macrophage colony-stimulating factor receptor binding | IL34;STAP1;CSF1 |
Il34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il34 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il34.
ATXN1
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewIL34 has shown good biocompatibility and safety in related experiments.
When using IL34 for experiments, the experimental conditions and results are highly repeatable.
Quality is stable and reliable, with no significant differences between batches.
Q&As (6)
Ask a questionThere are no clear studies showing the effect of IL34 on tumor prognosis.
Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.
May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.
No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.
Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.
The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.
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