Il34
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Official Full Name
interleukin 34
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Background
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008] -
Synonyms
IL34; interleukin 34; IL-34; C16orf77; interleukin-34;
- Involved Pathway
- Protein Function
- Interacting Protein
- Il34 Related Gene Family
- Il34 Related Research Area
Il34 involved in several pathways and played different roles in them. We selected most pathways Il34 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Il34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Il34 has several biochemical functions, for example, cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il34 itself. We selected most functions Il34 had, and list some proteins which have the same functions with Il34. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | GPI;Ifna11;CSF1B;NAMPT;IL23;TSLP;GDF10;IFNA3;IL17A |
| growth factor activity | BMP2B;CD320;GDF11;MIA1;F2;RABEP2;AMELX;VEGFAA;TGFB3 |
| macrophage colony-stimulating factor receptor binding | CSF1;IL34;STAP1 |
Il34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il34 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il34.
ATXN1
- Q&As
- Reviews
Q&As (6)
Ask a questionThere are no clear studies showing the effect of IL34 on tumor prognosis.
Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.
May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.
No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.
Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.
The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.
Customer Reviews (3)
Write a reviewIL-34 has good structural stability under suitable storage conditions, which can maintain its structural integrity and functional activity, and its preservation and stability are very important in the process of production and use. -
Through proper purification steps and process control, high purity IL-34 can be obtained, which can maximize the removal of impurities and ensure the quality of the product. -
This is expressed in different types of cells, so methods for producing IL-34 need to be tailored to specific cell types and subtypes to meet the needs of different uses. -
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