Recombinant Full Length Human IL4R Protein
Cat.No. : | IL4R-5681HF |
Product Overview : | Human IL4R full-length ORF (NP_001008699.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 25.6 kDa |
Protein Length : | 360 amino acids |
AA Sequence : | MGWLCSGLLFPVSCLVLLQVASSGN MKVLQEPTCVSDYMSISTCEWKMNG PTNCSTELRLLYQLVFLLSEAHTCI PENNGGAGCVCHLLMDDVVSADNYT LDLWAGQQLLWKGSFKPSEHVKPRA PGNLTVHTNVSDTLLLTWSNPYPPD NYLYNHLTYAVNIWSENDPADFRIY NVTYLEPSLRIAASTLKSGISYRAR VRAWAQCYNTTWSEWSPSTKWHNSN IC |
Applications : | Antibody Production Functional Study Compound Screening |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | IL4R interleukin 4 receptor [ Homo sapiens ] |
Official Symbol : | IL4R |
Synonyms : | IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA; |
Gene ID : | 3566 |
mRNA Refseq : | NM_000418 |
Protein Refseq : | NP_000409 |
MIM : | 147781 |
UniProt ID : | P24394 |
Products Types
◆ Recombinant Protein | ||
IL4R-5180H | Recombinant Human IL4R Protein | +Inquiry |
IL4R-5179H | Recombinant Human IL4R Protein, GST-tagged | +Inquiry |
IL4R-331H | Recombinant Human IL4R Protein, His-tagged | +Inquiry |
IL4R-330C | Recombinant Cynomolgus monkey IL4R Protein, Fc-tagged | +Inquiry |
IL4R-2437P | Recombinant Pig IL4R Protein (33-240 aa), His-sumostar-tagged | +Inquiry |
◆ Lysates | ||
IL4R-2719HCL | Recombinant Human IL4R cell lysate | +Inquiry |
IL4R-1051RCL | Recombinant Rat IL4R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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