Recombinant Rat Il4r protein, His-tagged

• Cat.No.: Il4r-2131R
• Product Overview: Recombinant Rat Il4r aa. (Ile26~Arg232 (Accession # Q63257)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.1kDa
• Protein length: Ile26~Arg232 (Accession # Q63257)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Il4r interleukin 4 receptor [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Il4r
• Synonyms: Ddt; D-dopachrome tautomerase; C78655; D-dopachrome decarboxylase
• Gene ID: 25084
• mRNA Refseq: NM_133380.2
• Protein Refseq: NP_596871.2
• UniProt ID: Q63257

Reviews

06/30/2022

Easy to attach to the surface of cells or materials.

09/29/2021

It has growth factor activity to promote cell growth and proliferation.

02/27/2019

In animals or humans caused by the prone production of antibodies.

Q&As

How about function of IL4R?

IL4R is a synthetic protein that mimics the IL-4 signaling pathway in nature and binds to the IL-4 receptor in cells, which can be used to study the IL-4 signaling pathway and related diseases.

What is the production technology of IL4R?

Common IL4R production technologies include prokaryotic expression systems and mammalian cell expression systems.

Which application of IL4R in tumor therapy?

This protein is used in tumor immunotherapy, which can promote anti-tumor immune response and enhance the anti-tumor effect of cytotoxic T lymphocytes.

In what fields does IL4R have applications?

It is mainly used in immunology, drug research and other fields. It is also widely used in vaccines, biotechnology, cancer treatment and so on.

Are there have application of IL4R in the treatment of asthma?

IL4R is used to treat severe pheochromocytome-induced aerodoritis and was approved by the FDA as the first drug to treat this disease.

Can IL4R be administered orally?

IL4R cannot generally be administered orally, and needs to be administered by injection or intravenous drip.