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Recombinant Human CCL20 Protein (70 aa)
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Cat.No. : | CCL20-327C Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human MIP-3α/CCL20 produced in E. coliis a single non-glycosylated polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-3α/CCL20has a molecular mass of 8.0 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
Description : | Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus. It can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. |
Source : | E. coli |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | The EC50 value of humanMIP-3 alpha/CCL20 on Ca^2+ mobilization assay in CHO-K1/Gα15/hCCR6 cells (human Gα15 and human CCR6 stably expressed in CHO-K1 cells) is less than 200 ng/mL. |
Molecular Mass : | 8.0 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 70 |
AA Sequence : | ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant Human MIP- 3α/CCL20 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, recombinant human MIP-3α/CCL20 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against 53mM Na2HPO4, 147 mM NaH2PO4, 300 mM NaCl, pH6.5. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | CCL20 chemokine (C-C motif) ligand 20 [ Homo sapiens ] |
Official Symbol : | CCL20 |
Synonyms : | CCL20; chemokine (C-C motif) ligand 20; SCYA20, small inducible cytokine subfamily A (Cys Cys), member 20; C-C motif chemokine 20; CKb4; exodus 1; LARC; MIP 3a; ST38; exodus-1; MIP-3-alpha; CC chemokine LARC; beta chemokine exodus-1; beta-chemokine exodus-1; small-inducible cytokine A20; macrophage inflammatory protein 3 alpha; liver and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 20; MIP3A; MIP-3a; SCYA20; |
Gene ID : | 6364 |
mRNA Refseq : | NM_001130046 |
Protein Refseq : | NP_001123518 |
MIM : | 601960 |
UniProt ID : | P78556 |
◆ Recombinant Protein
CCL20-073C | Recombinant Human CCL20 Protein (70 aa) | +Inquiry |
CCL20-218C | Recombinant Human CCL20 Protein (70 aa) | +Inquiry |
CCL20-0624H | Recombinant Human CCL20 Protein, GST-Tagged | +Inquiry |
CCL20-516H | Recombinant Human CCL20 Protein, MIgG2a Fc-tagged | +Inquiry |
Ccl20-170C | Recombinant Rat Ccl20 Protein (71 aa) | +Inquiry |
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◆ Lysates
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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