Recombinant Human CXCL16 Protein, His-tagged

• Cat.No.: CXCL16-882H
• Product Overview: Recombinant Human CXCL16 Protein (Asn30-Thr254) with His tag was expressed in 293F.

Specification

• Description: Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to interferon-gamma; and response to tumor necrosis factor. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma.
• Source: HEK293F
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.0 kDa; Accurate Molecular Mass: 36-40 kDa
• Protein length: Asn30-Thr254
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: CXCL16 chemokine (C-X-C motif) ligand 16 [ Homo sapiens (human) ]
• Official Symbol: CXCL16
• Synonyms: CXCL16; chemokine (C-X-C motif) ligand 16; C-X-C motif chemokine 16; CXC chemokine ligand 16; CXCLG16; SR PSOX; SRPSOX; small-inducible cytokine B16; transmembrane chemokine CXCL16; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX
• Gene ID: 58191
• mRNA Refseq: NM_001100812
• Protein Refseq: NP_001094282
• MIM: 605398
• UniProt ID: Q9H2A7

Reviews

02/16/2022

Great protein crystallization services, pivotal for structural biology research.

05/09/2021

Swift protein sequencing, crucial for protein identification.

07/24/2018

Invaluable protein-protein interaction assays, integral to our research.

Q&As

How does CXCL16 function as both a chemokine and an adhesion molecule in immune cell recruitment and interaction?

CXCL16 acts as both a chemokine and adhesion molecule, guiding immune cell recruitment and facilitating cell-cell interactions.

How does CXCL16 influence the progression of inflammatory and autoimmune diseases?

CXCL16 influences inflammatory and autoimmune diseases, modulating immune cell recruitment and activation.

What is the impact of CXCL16 in tumor immunology, specifically in tumor infiltration by immune cells?

In tumor immunology, CXCL16 facilitates the infiltration of immune cells into tumors, affecting tumor immunity.

How do alterations in CXCL16 expression or signaling affect renal function and the progression of kidney diseases?

Changes in CXCL16 expression impact kidney function, potentially contributing to the development of renal diseases.

What role does CXCL16 play in the pathogenesis of atherosclerosis and cardiovascular diseases?

CXCL16 plays a role in atherosclerosis by recruiting immune cells to arterial walls, influencing plaque formation.

What are the mechanisms by which CXCL16 modulates the migration and activation of T cells and dendritic cells?

CXCL16 regulates T cell and dendritic cell migration and activation, playing a key role in immune responses.

How does CXCL16 contribute to the immune response against pathogens, particularly in viral infections?

CXCL16 boosts the immune response to pathogens, especially in viral infections, by attracting immune cells.