Recombinant Human FGF19 Protein (Gly4-Lys216), His tagged
| Cat.No. : | FGF19-3332H |
| Product Overview : | Recombinant human FGF19 (Gly4-Lys216) protein fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. It interacts with KL and KLB directly. However, it interacts with FGFR4 in the presence of heparin, KL or KLB. FGF19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. It also stimulates glucose uptake in adipocytes. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Molecular Mass : | 25.14 kDa |
| Protein Length : | Gly4-Lys216 |
| Purity : | >90 % as determined by SDS-PAGE. |
| Notes : | For research use only. |
| Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
| Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
| Reconstitution : | Reconstitute in sterile water for a stock solution. |
| Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Gene Name : | FGF19 fibroblast growth factor 19 [ Homo sapiens (human) ] |
| Official Symbol : | FGF19 |
| Synonyms : | FGF19; fibroblast growth factor 19; FGF-19; |
| Gene ID : | 9965 |
| mRNA Refseq : | NM_005117 |
| Protein Refseq : | NP_005108 |
| MIM : | 603891 |
| UniProt ID : | O95750 |
Products Types
| ◆ Recombinant Protein | ||
| FGF19-032H | Recombinant Human FGF19 Protein | +Inquiry |
| FGF19-121F | Active Recombinant Human FGF19 Protein (195 aa) | +Inquiry |
| FGF19-4109H | Recombinant Human FGF19 Protein, GST-tagged | +Inquiry |
| FGF19-906H | Recombinant Human FGF19 Protein, His (Fc)-Avi-tagged | +Inquiry |
| FGF19-1485H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| FGF19-6244HCL | Recombinant Human FGF19 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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