Active Recombinant Human FGF9 Protein

• Cat.No.: FGF9-042H
• Product Overview: The mature recombinant human FGF-9 protein consists of 207 amino acids (2-208) without tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
• Source: E. coli
• Species: Human
• Bio-activity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 1-5 ng/mL.
• Molecular Mass: 23.4 kDa
• Product-Related Proteins: 2-208
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: FGF9 fibroblast growth factor 9 [ Homo sapiens (human) ]
• Official Symbol: FGF9
• Synonyms: FGF9; fibroblast growth factor 9; GAF; FGF-9; SYNS3; HBFG-9; HBGF-9; fibroblast growth factor 9; Names; fibroblast growth factor 9 (glia-activating factor); heparin-binding growth factor 9
• Gene ID: 2254
• mRNA Refseq: NM_002010
• Protein Refseq: NP_002001
• MIM: 600921
• UniProt ID: P31371